Split Scripts for Pediatric Supracondylar Fracture Repairs

NCT05372133 | Completed

• 1 other identifier: 1000079222
• Study Type: interventional
• Target: 175
• Locations: 1 country
• Sites: 1

Brief Summary

This study is designed to test the hypothesis that increased electronic order-set compliance and focused education will decrease the amount of unconsumed opioid entering and remaining in the home after pediatric supracondylar fracture repair The proposed study will address the hypothesis with the following objectives:

1. 1.investigators will increase compliance with previously implemented standardized precision-based electronic discharge order sets;
2. 2.investigators will introduce part-fill opioid prescriptions for supracondylar fracture repairs;
3. 3.investigators will increase parental compliance with home administration of simple (non-opioid) analgesics;
4. 4.investigators will decrease opioid amount remaining in the home pre and post 3-week follow up.

Conditions

Pain, Postoperative

Outcome Measures

Primary Outcomes (1)

• Amount of morphine milligram equivalents (MME) used at home per SCF patient between July 2022 and October 2023

  Recording of how much morphine (mgs or doses) was used at home following supracondylar fracture repair surgery

  3 days following discharge from hospital

Secondary Outcomes (3)

• Compliance with orders for home use of acetaminophen and ibuprofen per SCF patient between July 2022 and October 2023

  3 days following discharge from hospital

• Amount of morphine milligram equivalents (MME) returned to pharmacy per SCF patient between July 2022 and October 2023

  3 weeks following discharge (aligns with pin/wire removal at fracture clinic)

• Healthcare provider compliance to discharge order set

  Up to 100 weeks

Study Arms (1)

Split Script

EXPERIMENTAL

Participants will receive four doses initially, with opportunity to obtain four additional doses if required

Drug: Morphine

Interventions

Morphine DRUG

Children will be provided with morphine for at-home pain management following supracondylar fracture repair

Also known as: Opioid

Split Script

Eligibility Criteria

• Age: 1 Month - 18 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Patients with Type II or Type III supracondylar fractures undergoing surgical wire placement or pinning that return to fracture clinic at three weeks for removal of pins/wires.

You may not qualify if:

• Patients who are not prescribed morphine following a supracondylar fracture repair surgery

Sponsors & Collaborators

• The Hospital for Sick Children: lead

Study Sites (1)

The Hospital for Sick Children

Toronto, Ontario, M5G 1X8, Canada

Location

MeSH Terms

Conditions

Pain, Postoperative

Interventions

Morphine; Analgesics, Opioid

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Intervention Hierarchy (Ancestors)

Morphine Derivatives; Morphinans; Opiate Alkaloids; Alkaloids; Heterocyclic Compounds; Heterocyclic Compounds, Bridged-Ring; Heterocyclic Compounds, 4 or More Rings; Heterocyclic Compounds, Fused-Ring; Phenanthrenes; Polycyclic Aromatic Hydrocarbons; Polycyclic Compounds; Narcotics; Central Nervous System Depressants; Physiological Effects of Drugs; Pharmacologic Actions; Chemical Actions and Uses; Analgesics; Sensory System Agents; Peripheral Nervous System Agents; Central Nervous System Agents; Therapeutic Uses

Study Officials

• Conor Mc Donnell

  The Hospital for Sick Children

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator, Associate Professor

Study Record Dates

• First Submitted: February 15, 2022
• First Posted: May 12, 2022
• Study Start: August 11, 2022
• Primary Completion: August 18, 2023
• Study Completion: August 18, 2023
• Last Updated: November 21, 2023

Record last verified: 2023-11

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)