Comparative Clinical and Radiographical Evaluation of Treatment of Angular Bone Defect Related to Over Erupted Tooth Using GTR Followed by Orthodontic Intrusion Versus Orthodontic Intrusion Followed by GTR

NCT05371418 | Completed

• 1 other identifier: 3333
• Study Type: interventional
• Target: 10
• Locations: 1 country
• Sites: 1

Brief Summary

Occlusal prematurity leading to loss of vertical stopping points between teeth can lead to teeth over eruption creating abnormal contact area which favors food accumulation and plaque retention. All these factors can lead to gingival inflammation and bone loss which may be worsen by abnormal occlusal force. Thus, orthodontic evaluation and treatment with periodontic therapy is mandatory to achieve proper treatment. Aim of the work: To evaluate and compare clinically and radiographically between effect of guided tissue regeneration (GTR) followed by orthodontic intrusion versus orthodontic intrusion followed by GTR in treatment of over erupted tooth with angular bone loss

Conditions

Bone Loss; Occlusion

Keywords

overerupted tooth; angular bone loss; orthodontic intrusion

Outcome Measures

Primary Outcomes (2)

• the effect of GTR followed by OI in G1and OI followed by GTR in G2 evaluated clinically regarding pocket depth and tooth mobility

  pocket depth will be measured by mm, and tooth mobility with giving scoreM0: Physiological mobility,M1: Slightly increased mobility,M2: Definitive considerable increase in mobility but no impairment of function, M3: Extreme mobility, loose tooth that would be incompatible in function. these measurements were done prior starting phase one, one month after finishing phase one (Re-evaluation phase) and at six- and 12-months post starting either GTR or orthodontic intrusion (OI)

  12-15 months

• the effect of GTR followed by OI in G1and OI followed by GTR in G2 evaluated radiographically by cone beam computed tomography (CBCT) regarding bone defect area bymm2 and defect area dimensional changes by mm2

  the defect area was measured by mm2 at re-evaluation phase, 6 months post GTR in G1 or OI in G2 and after one year from re-evaluation phase in both groups and defect area dimensional changes by mm2 which was evaluated by subtracting value of bone area at 6 months post GTR in G1 or OI in G2 from bone area at Re-evaluation and and subtracting bone area at one year from re-evaluation from bone area at 6 months post GTR in G1 or OI in G2

  12-15 months

Secondary Outcomes (2)

• the effect of GTR followed by OI in G1and OI followed by GTR in G2 evaluated clinically regarding bleeding upon probing

  12-15 months

• the effect of GTR followed by OI in G1and OI followed by GTR in G2 evaluated radiographically using CBCT regarding defect depth

  12-15 months

Study Arms (2)

guided regeneration (GTR) followed by orthodontic intrusion

EXPERIMENTAL

Ten over erupted teeth were selected with an angular bone loss with presence of their opposing for spilt mouth study aged from 20- 35 years old, were treated by GTR followed by Orthodontic intrusion

Procedure: surgical (guided tissue regeneration)

Orthodontic intrusion followed by GTR

EXPERIMENTAL

Ten over erupted teeth were selected with an angular bone loss with presence of their opposing for spilt mouth study aged from 20- 35 years old, were treated by orthodontic intrusion followed by GTR

Device: orthodontic intrusion followed by guided tissue regeneration GTR

Interventions

surgical (guided tissue regeneration) PROCEDURE

In group 1 (G1), ten teeth over erupted with angular bone loss were treated by guided tissue regeneration (GTR) followed by Orthodontic intrusion

Also known as: guided tissue regeneration

guided regeneration (GTR) followed by orthodontic intrusion

orthodontic intrusion followed by guided tissue regeneration GTR DEVICE

. In group 2 (G2), ten teeth over erupted with angular bone loss were treated by Orthodontic intrusion (OI) followed by guided tissue regeneration (GTR)

Also known as: orthodontic intrusion

Orthodontic intrusion followed by GTR

Eligibility Criteria

• Age: 20 Years - 35 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Over erupted tooth with angular bone loss with presence of opposing
• Mobility doesn't exceed grade two
• No gingival recession more than 3mm

You may not qualify if:

• Systematic diseases that complicate oral surgery such as hyperparathyroidism, bleeding disorders,....etc.
• Smokers
• Patients with negative attitude towards oral hygiene

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Rehab Fouad Ghouraba

Tanta, Grabia, 3111, Egypt

Location

MeSH Terms

Conditions

Bone Diseases, Metabolic; Bites and Stings

Interventions

Surgical Procedures, Operative; Guided Tissue Regeneration

Condition Hierarchy (Ancestors)

Bone Diseases; Musculoskeletal Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases; Poisoning; Chemically-Induced Disorders; Wounds and Injuries

Intervention Hierarchy (Ancestors)

Plastic Surgery Procedures

Study Officials

• Rehab F Ghouraba, PHD

  Tanta University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principle investigator

Study Record Dates

• First Submitted: January 12, 2022
• First Posted: May 12, 2022
• Study Start: September 10, 2020
• Primary Completion: October 11, 2021
• Study Completion: October 30, 2021
• Last Updated: May 12, 2022

Record last verified: 2022-05

Locations

EG (1)