National Registry and Cohort Study of Pulmonary Vascular Disease
NCPVD
1 other identifier
observational
1,000
1 country
13
Brief Summary
This is a observational、multicenter, prospective cohort study for patients with pulmonary hypertension (PH). The purposes of this study were to evaluate the etiology、clinical characteristics、treatment modalities, and outcomes of patients with PH；also to set up registration system of PH in China, to build a database of Chinese PH, to establish a web-based international standard data acquisition system for PH and a multicenter clinical research platform. The results of the study will provide a basis for the future national health policy for prevention and treatment of PH.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Mar 2022
Longer than P75 for all trials
13 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 29, 2022
CompletedFirst Submitted
Initial submission to the registry
May 5, 2022
CompletedFirst Posted
Study publicly available on registry
May 10, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 30, 2028
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 30, 2028
June 26, 2025
June 1, 2025
6.8 years
May 5, 2022
June 25, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
All-cause Death
5 years
Secondary Outcomes (1)
Number of Participants with Clinical Worsening
5 years
Study Arms (1)
1
All consecutive consenting patients diagnosed with PH according to specific hemodynamic criteria at participating institutions.
Interventions
The clinical course and disease management of pulmonary hypertension patients
Eligibility Criteria
Patients with Pulmonary Hypertension from China based PH centers.
You may qualify if:
- Newly diagnosed or previously diagnosed patients with PH.
- Documentation of mean pulmonary arterial pressure (mPAP) \>20 mm Hg by right heart catheterization, performed at any time prior to study enrollment.
You may not qualify if:
- Have not had documentation of hemodynamic criteria for PH by right heart catheterization at some time preceding study entry and following development of symptoms associated with PH.
- Do not meet the required hemodynamic criteria for entry into the study.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (13)
Guangdong Provincial Peoples Hospital
Guangzhou, Guangdong, China
Nanjing First Hospital
Nanjing, Jiangsu, 210006, China
General Hospital of Tianjin Medical University
Tianjin, Tianjin Municipality, China
Beijing Anzhen Hospital of Capital Medical University
Beijing, China
China-japan Friendship Hospital
Beijing, China
Xiangya Second Hospital, Central South University
Changsha, China
West China Hospital, Sichuan University
Chendu, China
Nanjing Drum Tower Hospital
Nanjing, China
General Hospital of Northen Theater of Command
Shenyang, China
Tongji Hospital, Huazhong University of Science and Technology
Wuhan, China
Zhongnan Hospital of Wuhan University
Wuhan, China
First Affiliated Hospital of Xi'An Jiaotong University
Xi'an, China
First Hospital of Zhengzhou University
Zhengzhou, China
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 5 Years
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Vice President of Nanjing First Hospital, Director of Cardiovascular Department
Study Record Dates
First Submitted
May 5, 2022
First Posted
May 10, 2022
Study Start
March 29, 2022
Primary Completion (Estimated)
December 30, 2028
Study Completion (Estimated)
December 30, 2028
Last Updated
June 26, 2025
Record last verified: 2025-06