NCT05364398

Brief Summary

To assess the clinical outcome in patients who had ACL reconstruction with preservation of the remnant and compare it with patients in whom the stump was resected

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Apr 2017

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2017

Completed
3.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2020

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2020

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

May 3, 2022

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 6, 2022

Completed
Last Updated

November 20, 2025

Status Verified

November 1, 2025

Enrollment Period

3.1 years

First QC Date

May 3, 2022

Last Update Submit

November 18, 2025

Conditions

Knee Ligament Injury

Keywords

Anterior cruciate ligament reconstructiontibial stumpstump preservationknee proprioception.

Outcome Measures

Primary Outcomes (5)

  • Knee stability

    KT-1000 Arthrometer

    2 years

  • Knee proprioception

    Passive angle reproduction test

    2 years

  • Lysholm score

    2 years

  • Tegner activity score

    2 years

  • IKDC score

    2 years

Study Arms (2)

ACL reconstruction with stump preservation

ACTIVE COMPARATOR
Procedure: ACL reconstruction

ACL reconstruction with stump resection

ACTIVE COMPARATOR
Procedure: ACL reconstruction

Interventions

ACL reconstructionPROCEDURE

Use of hamstring tendons graft to replace the torn ACL and being passed and fixed through the femoral and tibial sides

ACL reconstruction with stump preservationACL reconstruction with stump resection

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • patients with torn ACL within 6 months

You may not qualify if:

  • Old ACL injury Multi-ligamentous knee injuries Mal-alignments

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kasr Alainy, Cairo University

Cairo, 11562, Egypt

Location

Related Publications (1)

  • El-Desouky MA, Ezzat M, Abdelrazek BH. Clinical outcomes in stump-preserving versus stump-sacrificing anterior cruciate ligament reconstruction; a randomized controlled study. BMC Musculoskelet Disord. 2022 Jul 23;23(1):703. doi: 10.1186/s12891-022-05665-3.

    PMID: 35870924DERIVED

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor of Orthopedic surgery

Study Record Dates

First Submitted

May 3, 2022

First Posted

May 6, 2022

Study Start

April 1, 2017

Primary Completion

April 30, 2020

Study Completion

September 1, 2020

Last Updated

November 20, 2025

Record last verified: 2025-11

Locations

EG(1)