NCT05363735

Brief Summary

Cesarean Section Scar Defect(CSD) is one of the complications after cesarean section. CSD will cause many long term complications, such as abnormal uterine bleeding, infertility, uterine scar pregnancy and uterine rupture. Transvaginal ultrasound was used to detect uterine scar defects commonly. Ultrasound elastography is a modern imaging technique that has developed rapidly in recent years. Thus, this study intend to investigate the application of Ultrasound Elastography in Cesarean Section Scar Defect.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Jun 2022

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 19, 2022

Completed
2 months until next milestone

First Posted

Study publicly available on registry

May 6, 2022

Completed
26 days until next milestone

Study Start

First participant enrolled

June 1, 2022

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2024

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2025

Completed
Last Updated

April 19, 2024

Status Verified

May 1, 2022

Enrollment Period

2.1 years

First QC Date

March 19, 2022

Last Update Submit

April 17, 2024

Conditions

Outcome Measures

Primary Outcomes (4)

  • thickness of the remaining muscular layer

    The thickness of the remaining muscular layer is measured by ultrasound

    4 weeks before vaginal repair of CSD

  • thickness of the remaining muscular layer

    The thickness of the remaining muscular layer is measured by ultrasound

    12 weeks after vaginal repair of CSD

  • strain ratio (SR)

    the ratio of mean strain in the lesion to the adjacent background tissue

    4 weeks before vaginal repair of CSD

  • strain ratio (SR)

    the ratio of mean strain in the lesion to the adjacent background tissue

    12 weeks after vaginal repair of CSD

Study Arms (1)

Ultrasound Elastography

Patients will be examined by ultrasound elastography.

Other: Ultrasound Elastography

Interventions

Patients will be examined by ultrasound elastography.

Ultrasound Elastography

Eligibility Criteria

Age18 Years - 40 Years
Sexfemale
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

women who were diagnosed with CSD

You may qualify if:

  • Clearly diagnosed with CSD
  • No serious medical problems (important viscera function in the normal range). uterine fibroids no more than 5cm
  • Sign the informed consent.

You may not qualify if:

  • Indefinite diagnosis.
  • Malignant tumors.
  • With severe medical problems (severe liver disease, kidney disease, respiratory diseases, heart disease or uncontrolled diabetes, epilepsy, etc., dysfunction of important organs).
  • Pregnant.
  • Mental diseases.
  • Unwilling to comply with the research plan.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine

Shanghai, Shanghai Municipality, 200092, China

Location

Study Officials

  • Wang Xipeng, Dr

    Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

    STUDY DIRECTOR
0

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 19, 2022

First Posted

May 6, 2022

Study Start

June 1, 2022

Primary Completion

June 30, 2024

Study Completion

June 30, 2025

Last Updated

April 19, 2024

Record last verified: 2022-05

Locations