Functional Prognosis of Post-operative Patients With Cerebral Small Vascular Disease(CSVD)
Association Between Postoperative Cerebral Vascular Complication and Functional Prognosis and Cerebral Small Vascular Disease (CSVD) After Thoracic Surgery : an Exploratory Study
1 other identifier
observational
212
1 country
1
Brief Summary
The investigators perform a retro-prospective exploratory cohort study among patients 65 to 85 years old with pre-operative head MRI result after thoracic surgery in Renji Hospital Affiliated to Shanghai Jiaotong University from November 2020 to December 2021. Perioperative data were collected, including preoperative general condition, laboratory examination, auxiliary examination (blood routine, blood coagulation, liver and kidney function, etc.), perioperative indicators （use of anesthetics, anesthetic time, blood pressure, etc.）, postoperative cerebral function follow-up and occurrence of cerebral vascular complications (brain infarction, brain bleed, etc.) of patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2022
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 29, 2022
CompletedStudy Start
First participant enrolled
January 31, 2022
CompletedFirst Posted
Study publicly available on registry
May 4, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 31, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
January 31, 2023
CompletedMay 4, 2022
April 1, 2022
1 year
January 29, 2022
April 28, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
Incidence of postoperative overt stroke
Postoperative overt stroke detected by MRI of the brain
1 year after surgery
Secondary Outcomes (2)
Physical function after surgery as assessed using Activities of Daily Living (iADL) Scale
1 year after surgery
Physical function after surgery as assessed using the Modified Rankin Scale
1 year after surgery
Eligibility Criteria
all postoperative patients between 65 and 85 years old with pre-operative brain MRI results in Renji Hospital Affiliated to Shanghai Jiaotong University from November 2020 to December 2021 after thoracic surgery
You may qualify if:
- ≤age\<85
- after thoracic surgery
- finish pre-operative brain MRI
You may not qualify if:
- mental illness
- existing dementia and other diseases: Alzheimer disease, dementia, Parkinson's disease, Huntington's disease, systemic lupus erythematosus, etc.
- previous cerebral infarction or hemorrhage
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- RenJi Hospitallead
Study Sites (1)
Renji Hospital, Shanghai Jiao Tong University, School of Medicine
Shanghai, Shanghai Municipality, 200127, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
January 29, 2022
First Posted
May 4, 2022
Study Start
January 31, 2022
Primary Completion
January 31, 2023
Study Completion
January 31, 2023
Last Updated
May 4, 2022
Record last verified: 2022-04