NCT05353023

Brief Summary

Using data from the French National Uniform Hospital Discharge Database (systematically collecting administrative and medical information related to all hospitalized patients in France for care reimbursement purposes), the present study retrospectively assesses the activity of the French Intensive Care Unit (ICU)(1,594,801 ICU admissions):

  • In-ICU and in-hospital mortality rates
  • Length of stay in ICU and hospital
  • Mortality-associated factors during the study period.
  • Number of organ failures
  • Bed occupancy,
  • Regional variations in previous indicators

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,594,801

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2013

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2013

Completed
9.3 years until next milestone

First Submitted

Initial submission to the registry

April 25, 2022

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 29, 2022

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2023

Completed
Last Updated

December 4, 2025

Status Verified

April 1, 2022

Enrollment Period

11 years

First QC Date

April 25, 2022

Last Update Submit

November 26, 2025

Conditions

Critical IllnessIntensive Care Unit

Outcome Measures

Primary Outcomes (6)

  • Evolution in mortality rate

    evolution of the mortality rate of ICU patients over the study period (2013-19)

    from January 1st, 2013, to December 31st, 2019

  • Evolution in organ failure rate

    evolution of the organ failure rate of ICU patients over the study period (2013-19)

    from January 1st, 2013, to December 31st, 2019

  • Evolution in ICU stay

    evolution of the ICU stay of ICU patients over the study period (2013-19)

    from January 1st, 2013, to December 31st, 2019

  • Evolution in SAPS (Simplified Acute Physiology Score) II score at admission

    evolution of the SAPS II score at admission of ICU patients over the study period (2013-19)

    from January 1st, 2013, to December 31st, 2019

  • Evolution in age at admission

    evolution of the age at admission of ICU patients over the study period (2013-19)

    from January 1st, 2013, to December 31st, 2019

  • Evolution in sex ratio

    evolution of the sex ratio of ICU patients over the study period (2013-19)

    from January 1st, 2013, to December 31st, 2019

Secondary Outcomes (4)

  • Proportion of patients admitted in ICU with at least 2 different organ failures

    from January 1st, 2013, to December 31st, 2019

  • - Proportion of patients admitted in ICU with a SAPS II score over 15 and with a specific ICU supportive therapy

    from January 1st, 2013, to December 31st, 2019

  • Factors Associated with in-ICU mortality

    from January 1st, 2013, to December 31st, 2019

  • Regional variations

    from January 1st, 2013, to December 31st, 2019

Study Arms (1)

ICU ADMISSION

All patients admitted in a French intensive care unit over a 7-year period (2013 to 2019) using the French National Uniform Hospital Discharge Database (PMSI)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All adults patients admitted in French ICU between January 1st, 2013, to December 31st, 2019

You may qualify if:

  • All adults patients admitted in French ICU between January 1st, 2013, to December 31st, 2019

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Intensive care Unit CHU Nîmes

Nîmes, 30029, France

Location

Related Publications (1)

  • Boulet N, Boussere A, Mezzarobba M, Sofonea MT, Payen D, Lipman J, Laupland KB, Rello J, Lefrant JY, Muller L, Roger C, Pirracchio R, Mura T, Boudemaghe T. Intensive Care Unit activity in France from the national database between 2013 and 2019: More critically ill patients, shorter stay and lower mortality rate. Anaesth Crit Care Pain Med. 2023 Oct;42(5):101228. doi: 10.1016/j.accpm.2023.101228. Epub 2023 Apr 7.

    PMID: 37031815RESULT

MeSH Terms

Conditions

Critical Illness

Condition Hierarchy (Ancestors)

Disease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Jean Yves LEFRANT

    Centre Hospitalier Universitaire de Nīmes

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 25, 2022

First Posted

April 29, 2022

Study Start

January 1, 2013

Primary Completion

December 31, 2023

Study Completion

December 31, 2023

Last Updated

December 4, 2025

Record last verified: 2022-04

Data Sharing

IPD Sharing
Will not share

Locations

FR(1)