Diagnosis of Heart Failure in Chronic Obstructive Pulmonary Disease Using the Lung Ultrasound

NCT05352490 | Completed

• 1 other identifier: Lung ultrasound, COPD, HF
• Study Type: observational
• Target: 350
• Locations: 1 country
• Sites: 1

Brief Summary

Acute Heart failure (AHF) is a common cause of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). This association is frequently underestimated with regard to the difficulty of clinical diagnosis. The investigators expect that the application of the lung ultrasound could be useful in this issue.

Conditions

Decompensated Heart Failure ; COPD Exacerbation; Dyspnea

Keywords

COPD Acute Heart Failure Lung ultrasound

Outcome Measures

Primary Outcomes (2)

• LUS in COPD patients whith pulmonory echography

  LUS measured whith pulmonory echography by the number of lines A and B.

  1day

• the accuracy of LUS in the diagnosis of heart failure in COPD patients

  the accuracy of LUS in the diagnosis of heart failure in patients with COPD measured by area under the roc curve

  1day

Study Arms (2)

HF-group

patients with AECOPD and acute heart failure

Diagnostic Test: calculate LUS score

non HF-group

patients with AECOPD without acute heart failure

Diagnostic Test: calculate LUS score

Interventions

calculate LUS score DIAGNOSTIC_TEST

calculate LUS score

HF-group; non HF-group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients with history of COPD admitted to the emergency departmet for dyspnea

You may qualify if:

• patients with history of COPD admitted to the emergency department for dyspnea non traumatic dyspnea

You may not qualify if:

• instable hemodynamic or neurological status non consent to participate in the study

Sponsors & Collaborators

• University of Monastir: lead

Study Sites (1)

Emergency Departement

Monastir, 5000, Tunisia

Location

Related Publications (1)

• Lajili F, Toumia M, Sekma A, Bel Haj Ali K, Sassi S, Zorgati A, Yaakoubi H, Youssef R, Grissa MH, Beltaief K, Mezgar Z, Khrouf M, Chamtouri I, Bouida W, Boubaker H, Msolli MA, Dridi Z, Boukef R, Nouira S. Value of Lung Ultrasound Sonography B-Lines Quantification as a Marker of Heart Failure in COPD Exacerbation. Int J Chron Obstruct Pulmon Dis. 2024 Aug 1;19:1767-1774. doi: 10.2147/COPD.S447819. eCollection 2024.

  PMID: 39108664 DERIVED

Related Links

• official department website

MeSH Terms

Conditions

Dyspnea

Condition Hierarchy (Ancestors)

Respiration Disorders; Respiratory Tract Diseases; Signs and Symptoms, Respiratory; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Nouira semir Nouira semir, professor

  Principal Investigator university

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: March 9, 2022
• First Posted: April 28, 2022
• Study Start: March 1, 2022
• Primary Completion: May 31, 2023
• Study Completion: May 31, 2023
• Last Updated: July 7, 2026

Record last verified: 2022-08

Locations

TU (1)