NCT05351632

Brief Summary

Postoperative complications should be reported systematically, objectively and reproducibly. The Clavien-Dindo Classification (CDC), first described in 2004, is the most popular classification system still in use today for assessing perioperative morbidity and mortality. In 2018, the European Association of Urology (EAU) validated this classification, which was originally defined for general surgery operations, for urological operations as well. There are aspects of the CDC that can be critical and weak. The CDC's main weakness is that in the vast majority of studies it only considers the most serious complications. Minor complications are often overlooked and the overall complication burden is therefore underestimated. Because of this vulnerability, it is difficult to compare complications from different patients. For example, it cannot be determined whether a patient with two Grade I complications has higher postoperative morbidity than a patient with one Grade II complication. To address these limitations, the Comprehensive Complications Index (CCI) was defined in 2013 as a new and more comprehensive scoring system for surgical complications. The CCI is essentially an index based on the CDC, but sums all postoperative complications by severity and scores them on an interval scale. It is scored from 0 (no complications) to 100 (patient's death) for each patient. CCI in Urology Practice; Validated for Radical Cystectomy, Radical Prostatectomy, Radical Nephroureterectomy, Partial Nephrectomy. In recent years, validation studies of this index have been carried out in endourological surgeries.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
644

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2022

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 22, 2022

Completed
6 days until next milestone

First Posted

Study publicly available on registry

April 28, 2022

Completed
3 days until next milestone

Study Start

First participant enrolled

May 1, 2022

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2023

Completed
Last Updated

April 28, 2022

Status Verified

April 1, 2022

Enrollment Period

12 months

First QC Date

April 22, 2022

Last Update Submit

April 22, 2022

Conditions

Keywords

Comprehensive Complications IndexPercutaneous NephrolithotomyComplication

Outcome Measures

Primary Outcomes (2)

  • The Comprehensive Complication Index

    The comprehensive complications index was proposed as a novel comprehensive scoring system for surgical complications in 2013. It's scoring complications on an interval scale between 0 (no complication) and 100 (death of the patient) for each patient.

    within 2 months post-procedure

  • Clavien-Dindo-Classification score

    The Clavien-Dindo-Classification (CDC), first described in 2004, is the most popular classification system for assessing perioperative morbidity and mortality.

    within 2 months post-procedure

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patient group over 18 years of age with kidney stones and no contraindications for PCNL

You may qualify if:

  • To have a medical indication for percutaneous kidney stone surgery
  • To have given consent to participate in the study
  • To be18 years of age or older

You may not qualify if:

  • To be under the age of 18
  • Not to have given consent to participate in the study
  • Not to have a medical indication for percutaneous kidney stone surgery
  • To Have an orthopedic disorder that prevents him from undergoing percutaneous kidney stone surgery
  • To have a hematological disorder that prevents percutaneous kidney stone surgery
  • To have a malignancy that prevents percutaneous kidney stone surgery
  • To have a serious cardiac and respiratory comorbidities that prevent percutaneous kidney stone surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Zonguldak Bülent Ecevit University, school of medicine

Zonguldak, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Postoperative Complications

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Reha GİRGİN, Assist.Prof.

    Zonguldak Bulent Ecevit University

    STUDY DIRECTOR

Central Study Contacts

Reha GİRGİN, Assist.Prof.

CONTACT

Yilören TANIDIR, Associ.Prof.

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
2 Months
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associ.Prof.

Study Record Dates

First Submitted

April 22, 2022

First Posted

April 28, 2022

Study Start

May 1, 2022

Primary Completion

April 30, 2023

Study Completion

April 30, 2023

Last Updated

April 28, 2022

Record last verified: 2022-04

Data Sharing

IPD Sharing
Will not share

Locations