NCT05344053

Brief Summary

The community-based precise management for patients with coronary artery disease study is a prospective, cluster-randomized, open-labeled trial. The purpose of this trial is to test whether a community-based precise management and rehabilitation model under the hierarchical medical system could help improve the cardiovascular risk factors control in patients with coronary artery disease. Additionally, the trial will also evaluate the impact of the model on major cardiovascular adverse events in patients with coronary artery disease.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
480

participants targeted

Target at P75+ for not_applicable coronary-artery-disease

Timeline
Completed

Started May 2022

Shorter than P25 for not_applicable coronary-artery-disease

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 19, 2022

Completed
6 days until next milestone

First Posted

Study publicly available on registry

April 25, 2022

Completed
6 days until next milestone

Study Start

First participant enrolled

May 1, 2022

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2023

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2023

Completed
Last Updated

May 6, 2022

Status Verified

May 1, 2022

Enrollment Period

1.1 years

First QC Date

April 19, 2022

Last Update Submit

May 4, 2022

Conditions

Keywords

Coronary Artery DiseaseRisk Factor ControlCommunity-based ManagementSecondary Prevention

Outcome Measures

Primary Outcomes (1)

  • Status of risk factors control of coronary artery disease

    A composite of not smoking, blood pressure\<140/90mmHg/\<130/80mmHg for patients with diabetes, HbA1c≤7%, LDL-C\<1.8mmol/L, antiplatelet therapy, and statins use.

    1 year

Secondary Outcomes (5)

  • All-cause death

    1 year

  • Readmission

    1 year

  • Myocardial infarction

    1 year

  • Coronary revascularization

    1 year

  • Stroke

    1 year

Study Arms (2)

Community-based precise management

EXPERIMENTAL
Other: Community-based precise management

Standard community-based management

ACTIVE COMPARATOR
Other: Standard community-based management

Interventions

The community-based precise management is a modified management strategy beyond the traditional standard community-based care under the hierarchical medical system of China. In the intervention arm, the community doctors receive training to improve their skills on coronary artery disease management. Patients will be under management for 1 year according to the strategies of community-based precise management and rehabilitation model.

Community-based precise management

The standard community-based management is the usual community-based care under the hierarchical medical system of China. In this arm, the community doctors will not receive any training on precise management strategies to improve their skills on coronary artery disease management, and patients will be under usual care for 1 year.

Standard community-based management

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with prior myocardial infarction
  • or receiving percutaneous coronary intervention or coronary artery bypass graft;
  • or coronary artery stenosis≥50% defined by coronary angiography or coronary CT angiography

You may not qualify if:

  • Refuse to sign the written informed consent;
  • Patients without the ability to take care of themselves;
  • Mental disorders;
  • Alcoholics or drug addicts;
  • Cannot be followed up for any reasons;
  • Life expectancy\<1 year due to non-cardiovascular reasons.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Infirmary of Industrial and Commercial Bank of China

Beijing, Beijing Municipality, 100037, China

RECRUITING

MeSH Terms

Conditions

Coronary Artery Disease

Condition Hierarchy (Ancestors)

Coronary DiseaseMyocardial IschemiaHeart DiseasesCardiovascular DiseasesArteriosclerosisArterial Occlusive DiseasesVascular Diseases

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Chief Physician, MD, PhD

Study Record Dates

First Submitted

April 19, 2022

First Posted

April 25, 2022

Study Start

May 1, 2022

Primary Completion

June 1, 2023

Study Completion

July 1, 2023

Last Updated

May 6, 2022

Record last verified: 2022-05

Locations