Dental Age Estimation by Different Methods in Patients With Amelogenesis Imperfecta

NCT05343247 | Completed

• 1 other identifier: 2021/76
• Study Type: observational
• Target: 416
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to investigate whether there is a significant difference in dental age between children with amelogenesis imperfecta (AI) and healthy controls using Cameriere European formula and London Atlas. If there is a significant difference in dental age between children with AI and healthy controls, it is aimed to create a new formula.

Conditions

Amelogenesis Imperfecta; Dental Age Estimation

Keywords

children; dental age estimation; amelogenesis imperfecta; chronological age; London Atlas; Cameriere European Formula

Outcome Measures

Primary Outcomes (2)

• Correlation coefficient of London Atlas method.

  Dental age of children with AI and healthy controls assessed by the correlation coefficient.

  day 1

• Correlation coefficient of Cameriere European formula.

  Dental age of children with AI and healthy controls assessed by the correlation coefficient.

  day 1

Secondary Outcomes (1)

• Dental age estimation in children with AI

  day 1

Study Arms (2)

Children with AI

Diagnostic Test: Cameriere method; Diagnostic Test: London Atlas method

Healthy controls with gender-age match

Diagnostic Test: Cameriere method; Diagnostic Test: London Atlas method

Interventions

Cameriere method DIAGNOSTIC_TEST

Cameriere et al. designed a quantitative approach through a formula based on sex and the ratio between length and apex opening measurements of each lower left tooth.

Children with AI; Healthy controls with gender-age match

London Atlas method DIAGNOSTIC_TEST

The London Atlas requires the user to assess the tooth development and eruption and then match it to one of the 31 pictures of age categories.

Children with AI; Healthy controls with gender-age match

Eligibility Criteria

• Age: 5 Years - 13 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Probability Sample

Study Population

This study was conducted on gender-age matched healthy control group of children aged 5-13 years, who applied to Istanbul University Faculty of Dentistry, Department of Pedodontics, had an AI record in their anamnesis, had panoramic radiographs in the archive of the Department of Oral and Maxillofacial Radiology, Istanbul University Faculty of Dentistry.

You may qualify if:

• years old
• Healthy children
• Children with AI
• Patients without missing left mandibular permanent teeth on panoramic radiography

You may not qualify if:

• Children older than 5 years old and younger than 14 years (children that cannot be assessed by the Willems and Cameriere method)
• Poor quality panoramic radiography
• Patients who have received orthodontic treatment
• Patients who received restorative or endodontic treatment

Sponsors & Collaborators

• Istanbul University: lead

Study Sites (1)

Istanbul University, Faculty of Dentistry

Istanbul, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Amelogenesis Imperfecta

Condition Hierarchy (Ancestors)

Developmental Defects of Enamel; Tooth Abnormalities; Stomatognathic System Abnormalities; Stomatognathic Diseases; Tooth Diseases; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: April 18, 2022
• First Posted: April 25, 2022
• Study Start: March 1, 2022
• Primary Completion: April 15, 2024
• Study Completion: April 23, 2024
• Last Updated: August 22, 2024

Record last verified: 2023-11

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)