NCT05341245

Brief Summary

Using Graphene oxide in the surgical management of periodontal intrabony defects.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
6

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started May 2022

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 22, 2022

Completed
1 month until next milestone

First Posted

Study publicly available on registry

April 22, 2022

Completed
9 days until next milestone

Study Start

First participant enrolled

May 1, 2022

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2023

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2023

Completed
Last Updated

April 22, 2022

Status Verified

April 1, 2022

Enrollment Period

1 year

First QC Date

March 22, 2022

Last Update Submit

April 17, 2022

Conditions

Periodontal Diseases

Outcome Measures

Primary Outcomes (2)

  • periodontal probing depth

    To evaluate the use of Graphene Oxide in the surgical management of intrabony periodontal defects regarding the changes in periodontal probing depth "measured in mm " using University of North Carolina periodontal probe( UNC 15 probe ).

    2 months

  • Clinical attachment level

    To evaluate the use of Graphene Oxide in the surgical management of intrabony periodontal defects regarding the changes in clinical attachment level "measured in mm " using University of North Carolina periodontal probe( UNC 15 probe )

    2 month

Secondary Outcomes (1)

  • Histomorphometric evaluation

    2 months

Study Arms (2)

Graphene oxide group

EXPERIMENTAL

The surgical defect will be managed by open flap debridement and application of Graphene oxide

Procedure: Graphene oxide and open flap debridement

Open flap group

OTHER

The surgical defect will be managed by open flap debridement

Procedure: Open flap debridement

Interventions

Graphene oxide and open flap debridementPROCEDURE

Using Graphene oxide with open flap debridement in management of periodontal intrabony defects in dogs

Graphene oxide group
Open flap debridementPROCEDURE

Using Open flap debridement in management of periodontal intrabony defects in dogs

Open flap group

Eligibility Criteria

Age1 Year - 2 Years
Sexmale
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • male dogs
  • months old with approximate weight of 20-30 kg and general good health will be used

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Periodontal Diseases

Interventions

graphene oxide

Condition Hierarchy (Ancestors)

Mouth DiseasesStomatognathic Diseases

Central Study Contacts

Zeiad Rashad

CONTACT

2001111309030Zeiadkhaled2010@gmail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

March 22, 2022

First Posted

April 22, 2022

Study Start

May 1, 2022

Primary Completion

May 1, 2023

Study Completion

June 1, 2023

Last Updated

April 22, 2022

Record last verified: 2022-04