Ilioinguinal/Iliohypogastric Block for Inguinal Hernia Repair

NCT05335837 | Unknown

• 1 other identifier: 119564
• Study Type: observational
• Target: 350
• Locations: 1 country
• Sites: 1

Brief Summary

Inguinal hernia have traditionally been done under general anesthesia. While safe, general anesthesia is associated with potential postoperative nausea/vomiting and drowsiness. Additionally, the recent COVID19 pandemic has heightened the precaution to avoid aerosol generating procedures (AGP) if possible. General anesthesia requires airway manipulation, thus necessitate performing an AGP. Recently, we began using peripheral nerve block and sedation as primary anesthetic technique for inguinal hernia repairs. While surgeon administered local anesthetic, also known as local infiltration, has been done for inguinal hernia repair, using specific nerve blocks and sedation has not been compared with general anesthesia. We believe the advantage of this novel technique can improve postoperative recovery. This retrospective study will compare the total hospital length of stay of those receiving nerve blocks and sedation as primary anesthetic techniques versus those with general anesthesia.

Conditions

Anesthesia

Outcome Measures

Primary Outcomes (1)

• Postoperative recovery time

  Time from exiting operating room to time ready for hospital discharge

  Time from exiting operating room to time ready for hospital discharge, up to 100 hours

Secondary Outcomes (7)

• Preoperative time

  Time from patient registration to entering operating room, up to 100 hours

• Intraoperative time

  Time from entering to exiting operating room, up to 100 hours

• Hospital length of stay

  Time from patient registration to ready for hospital discharge, up to 100 hours

• Postoperative nausea vomiting

  Time from exiting operating room to time ready for hospital discharge, up to 100 hours

• Severe pain

  Time from exiting operating room to time ready for hospital discharge, up to 100 hours

Study Arms (2)

General Anesthesia

patients received general anesthesia for inguinal hernia repair

Regional Anesthesia and Sedation

patients received ilioinguinal/iliohypogastric nerve blocks and sedation for inguinal hernia repair

Procedure: Regional Anesthesia and Sedation

Interventions

Regional Anesthesia and Sedation PROCEDURE

Preoperative ilioinguinal/iliohypogastric nerve block and moderate to deep intraoperative sedation.

Regional Anesthesia and Sedation

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patient

You may qualify if:

• years or older
• American Society of Anesthesiologists (ASA) Physical Status I to III
• Body Mass Index (BMI) less than 45
• Single hernia repair, elective, ambulatory surgery

You may not qualify if:

• Opioid dependence (30 mg oral morphine equivalents daily or more)
• History of malignant hyperthermia
• Pregnancy

Sponsors & Collaborators

• London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's: lead

Study Sites (1)

Cheng Lin

London, Ontario, n6c6a7, Canada

Location

MeSH Terms

Interventions

Anesthesia, Conduction

Intervention Hierarchy (Ancestors)

Anesthesia; Anesthesia and Analgesia

Central Study Contacts

Cheng Lin

CONTACT

5196858600; cheng.lin@lhsc.on.ca

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical Professor

Study Record Dates

• First Submitted: April 9, 2022
• First Posted: April 19, 2022
• Study Start: May 1, 2022
• Primary Completion: June 1, 2022
• Study Completion: July 1, 2022
• Last Updated: April 19, 2022

Record last verified: 2022-04

Locations

CA (1)