NCT05330936

Brief Summary

A randomized clinical trial with two groups. Group A Group B Group A is being treated with conventional Steroid combination ointment for the treatment of chronic Plaque Psoriasis. Group B is being treated with Cyanocobalamin in Avocado Oil cream for the treatment of chronic Plaque Psoriasis. Each group having 45 patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
90

participants targeted

Target at P75+ for early_phase_1

Timeline
Completed

Started Jan 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2021

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

March 23, 2022

Completed
23 days until next milestone

First Posted

Study publicly available on registry

April 15, 2022

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2022

Completed
Last Updated

May 24, 2023

Status Verified

May 1, 2023

Enrollment Period

1.7 years

First QC Date

March 23, 2022

Last Update Submit

May 22, 2023

Conditions

Plaque Psoriasis

Outcome Measures

Primary Outcomes (1)

  • Efficacy and tolerability of steroids as compared to Avacado Oil Cream

    Compariaon of Efficacy of Steroid combination ointment in the treatment of chronic Plaque Psoriasis

    12 weeks

Study Arms (2)

Group A

ACTIVE COMPARATOR

Steroid combination ointment in the treatment of chronic Plaque Psoriasis

Combination Product: Potent topical steroid

Group B

ACTIVE COMPARATOR

Cyanocobalamin in Avocado Oil cream in the treatment of chronic Plaque

Combination Product: Potent topical steroid

Interventions

Potent topical steroidCOMBINATION_PRODUCT

Cyanocobalamin in Avocado Oil Cream

Group AGroup B

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Age bracket (18-60 years)
  • Non psoriatic Arthritis
  • No oral Retinoids

You may not qualify if:

  • pregnancy
  • Malignancy
  • Body surface area involving \>50%

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

PakEmiratesMH

Rawalpindi, Punjab Province, 92, Pakistan

Location

Study Officials

  • Qamar ud din Khan, MBBS,FCPS

    Pak Emirates Military Hospital

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
early phase 1
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Randomized clinical trial
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Registrar Dermatology

Study Record Dates

First Submitted

March 23, 2022

First Posted

April 15, 2022

Study Start

January 1, 2021

Primary Completion

September 1, 2022

Study Completion

September 1, 2022

Last Updated

May 24, 2023

Record last verified: 2023-05

Data Sharing

IPD Sharing
Will not share

Locations

PA(1)