Work-To-Rest Ratios

NCT05327764 | Completed

• 1 other identifier: STUDY00006115
• Study Type: interventional
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of the study is to compare physiological responses to two hours of work adhering to two variations of a work-to-rest ratio in a hot environment.

Conditions

Hyperthermia

Outcome Measures

Primary Outcomes (2)

• Change in core body temperature

  Core body temperature is measured using a rectal thermistor

  Upon completion of 2 hours of the work protocol

• Change in heart rate

  Heart rate is measured using a telemetry strap

  Upon completion of 80 minutes of work

Study Arms (2)

40:20

ACTIVE COMPARATOR

Walking for 40 minutes, resting for 20

Other: Work to rest cycles of 40:20 minutes

20:10

EXPERIMENTAL

Walking for 40 minutes, resting for 20

Other: Work to rest cycles of 20:10 minutes

Interventions

Work to rest cycles of 40:20 minutes OTHER

Walking in a hot environment for 2 hours with repeated 40 minutes of work and 20 minutes of rest

40:20

Work to rest cycles of 20:10 minutes OTHER

Walking in a hot environment for 2 hours with repeated 20 minutes of work and 10 minutes of rest

20:10

Eligibility Criteria

• Age: 18 Years - 39 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Healthy 18-39 year old individuals
• Physically active

You may not qualify if:

• History of cardiovascular, metabolic, respiratory, neural, or renal disease
• Hypertensive or tachycardic during the screening visit (systolic blood pressure ≥ 140 mmHg, diastolic blood pressure ≥ 90 mmHg, resting heart rate ≥ 100 bpm)
• Taking medication or supplements with a known side effect of affecting physiologic responses to exercise (e.g., acetaminophen, beta blockers, statins, aspirin)
• Any form of tobacco or nicotine use in the past six months
• Current musculoskeletal injury impacting physical activity
• A positive pregnancy test at any point in the study
• Study physician discretion based on any other medical condition or medication

Sponsors & Collaborators

• State University of New York at Buffalo: lead

Study Sites (1)

University at Buffalo

Buffalo, New York, 14214, United States

Location

MeSH Terms

Conditions

Hyperthermia

Condition Hierarchy (Ancestors)

Body Temperature Changes; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Heat Stress Disorders; Wounds and Injuries

Study Officials

• Riana Pryor, PhD

  University at Buffalo

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Model Details: Randomized counterbalanced study

Study Record Dates

• First Submitted: March 26, 2022
• First Posted: April 14, 2022
• Study Start: March 21, 2022
• Primary Completion: November 5, 2023
• Study Completion: November 5, 2023
• Last Updated: November 9, 2023

Record last verified: 2023-11

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)