Evaluation of the Remineralizing Effect of Aloe Vera Versus Diode Laser for Management of Deep Carious Lesions.

NCT05327049 | Completed

• 1 other identifier: OPEN- 108-L
• Study Type: interventional
• Target: 45
• Locations: 1 country
• Sites: 1

Brief Summary

The present study will be performed to evaluate: The remineralizing effect of Aloe Vera versus Diode laser on deep carious dentin after selective caries removal.

Conditions

Deep Caries

Outcome Measures

Primary Outcomes (1)

• assessment of the remineralizing effect of aloe vera and diode laser on deep caries

  remineralisation will be assessed by radiodensity using digital radiography

  6 months

Study Arms (3)

no intervention

EXPERIMENTAL

No Intervention: conventional selective caries removal without treatment After taking the first sample of dentin, the cavity will be restored

Other: no intervention

diode laser treatment

EXPERIMENTAL

After selective caries removal the cavity was irradiated in contact mode with continuous wave of radiation through a 400µm flexible fiber that was inserted inside the cavity with a spiral continuous movement clockwise from the top to the floor and anti-clockwise in the reverse direction. Irradiation time was 15 seconds and repeated three times for 15 seconds interval with contact, pulsed mode and the output power was adjusted at 1.30 Watt.

Device: diode laser

Aloe Vera treatment

EXPERIMENTAL

After selective caries removal the lesions were treated with aloe Vera paste which was prepared by mixing aloe Vera powder by distilled water until a thick paste is formed. the paste was applied to the prepared floor by condenser to cover the remaining carious lesion

Dietary Supplement: Aloe Vera

Interventions

no intervention OTHER

treatment of deep carious lesions

no intervention

diode laser DEVICE

laser light for cavity disinfection

diode laser treatment

Aloe Vera DIETARY_SUPPLEMENT

herbal dietary supplement for treatment of deep carious lesions

Aloe Vera treatment

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Subject must have active deep carious lesion.
• clinical and radiographic examinations of carious lesions.

You may not qualify if:

• Teeth with pulpal involvement
• Teeth with abscess
• Teeth with pain or swelling
• Teeth with developmental disorders
• Teeth with adjacent soft tissue lesions
• patients with systemic illness will be excluded

Sponsors & Collaborators

• Al-Azhar University: lead

Study Sites (1)

Al-Azhar University

Naşr, Cairo Governorate, 11651, Egypt

Location

MeSH Terms

Interventions

Lasers, Semiconductor

Intervention Hierarchy (Ancestors)

Lasers; Optical Devices; Equipment and Supplies; Radiation Equipment and Supplies

Study Officials

• Maha Niazy, professor

  Al-Azhar University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant lecturer of operative dentistry

Study Record Dates

• First Submitted: April 6, 2022
• First Posted: April 14, 2022
• Study Start: February 1, 2021
• Primary Completion: October 1, 2021
• Study Completion: October 11, 2021
• Last Updated: April 14, 2022

Record last verified: 2022-04

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)