Comparison of Thyroid Volumes in Patients With and Without Endometrioma

NCT05323539 | Completed

• 1 other identifier: 1557/2021
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of our study is to evaluate whether there is a statistical difference between thyroid gland volume in patients with pathological diagnosis of endometriosis or endometrioma and in patients who underwent surgery for other gynecological reasons, and to reveal the presence of concomitant thyroid disease in these cases.

Conditions

Endometrioma; Thyroid

Outcome Measures

Primary Outcomes (1)

• Measuring Thyroid Volumes by ultrasonography

  Longitudinal and transverse scans are performed allowing the measurement of the depth, the width and the length of each lobe. The ellipsoid formula is used. The thyroid volume is the sum of the both lobes excluding isthmus. All measurements are performed bt one experienced radiologist.

  6 months

Study Arms (2)

Patients with endometrioma

ACTIVE COMPARATOR

Patients having a prediagnosis of surgically planned endometrioma occured this group.

Other: Evaluating Thyroid Volumes by ultrasonography

Control group

ACTIVE COMPARATOR

Patients who had planned gynecological surgery for a reason (ovarian cycts) other than endometrioma

Other: Evaluating Thyroid Volumes by ultrasonography

Interventions

Evaluating Thyroid Volumes by ultrasonography OTHER

The inclusion criteria are ; having a prediagnosis of surgically planned endometrioma and to undergo gynecological surgery for a reason other than endometriosis (control group). Among the patients with pre-diagnosis of endometriosis, who applied to our clinic during the study period and accepted to participate in the study, thyroid volumes will be measured by ultrasonography during the preoperative hospitalization. The pathological diagnosis of the patients will be confirmed and patients with different results will be excluded from the study (such as malignancy, endometriosis prediagnosis but different pathology detected etc.) In the same period, gynecological surgery was planned for another reason and patients without endometriosis will form the control group.

Also known as: routine blood tests, pathology data reports

Control group; Patients with endometrioma

Eligibility Criteria

• Age: 18 Years - 45 Years
• Gender Eligibility Details: having a prediagnosis of surgically planned endometrioma
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Prediagnosis of surgically planned endometrioma

You may not qualify if:

• Patients with goiteri,
• Patients with past or present autoimmune thyroid dysfunction,
• Patietns on treatment with thyroid hormones or drugs containing iodine.

Sponsors & Collaborators

• Adana City Training and Research Hospital: lead

Study Sites (1)

Adana City Education and Research Hospital

Adana, Merkez, 01100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Endometriosis; Thyroid Diseases

Condition Hierarchy (Ancestors)

Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases; Endocrine System Diseases

Study Officials

• Gulsum Uysal

  University of Heath and Sciences Adana City Training and Research Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SCREENING
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor Gulsum Uysal

Study Record Dates

• First Submitted: April 5, 2022
• First Posted: April 12, 2022
• Study Start: September 20, 2021
• Primary Completion: May 20, 2022
• Study Completion: July 20, 2022
• Last Updated: August 1, 2023

Record last verified: 2023-07

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)