GLUCOSAMINE/CHONDROITIN and PHYSICAL THERAPY EFFECTS ON OLDER POPULATION WITH KNEE OSTEOARTHRITIS
EFFECTS OF COMBINED GLUCOSAMINE/CHONDROITIN WITH STRUCTURED PHYSICAL THERAPY PROGRAM ON KNEE OSTEOARTHRITIS: A RANDOMIZED CONTROL TRAIL
1 other identifier
interventional
30
1 country
1
Brief Summary
to see the effect of glucosamine chondratin sulfate with and without physiotherapy in knee osteoarthritis
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable knee-osteoarthritis
Started Jul 2021
Shorter than P25 for not_applicable knee-osteoarthritis
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 26, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 25, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
March 25, 2022
CompletedFirst Submitted
Initial submission to the registry
March 26, 2022
CompletedFirst Posted
Study publicly available on registry
April 11, 2022
CompletedApril 11, 2022
April 1, 2022
8 months
March 26, 2022
April 4, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
WOMAC
higher score means worst patient condition and lower score means better
6 months
Secondary Outcomes (1)
SF-36
6 months
Study Arms (2)
control group
ACTIVE COMPARATORchondritin sulfate 1500/1200mg
experimental group
EXPERIMENTALchondritin sulfate plus physiotherapy
Interventions
Eligibility Criteria
You may qualify if:
- age \> 50 years with radiographic evidence of mild to moderate knee OA (Kellgren Lawrence grade II \& III 20) who met the ACR clinical 21,
- radiographic classification criteria or confirmation of mild to moderate radiographic evidence of knee OA from a personal physician
- not currently participating in another intervention study
You may not qualify if:
- dementia (Mini-Mental State Examination \[MMSE\]\< 24)
- active cancer other than skin cancer
- anemia (participants with an hematocrit (HCT)\< 32 (or a hemoglobin below10) were excluded due to possible inability to adequately exercise or the increased potential for increased risk for serious adverse cardiovascular events)
- severe renal insufficiency (serum creat\> 2)
- hepatic disease
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Muhammad Umar
Rawalpindi, Punjab Province, 46030, Pakistan
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
MUHAMMAD UMAR
the physiotherapy clinic
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Principal researcher
Study Record Dates
First Submitted
March 26, 2022
First Posted
April 11, 2022
Study Start
July 26, 2021
Primary Completion
March 25, 2022
Study Completion
March 25, 2022
Last Updated
April 11, 2022
Record last verified: 2022-04
Data Sharing
- IPD Sharing
- Will not share