NCT05321043

Brief Summary

Study objective: To clarify the risk of exposure to indirect contact and transmission of environmental objects during digestive endoscopy diagnosis and treatment for patients and medical staff, simulating by using Vitamin B2 solution. Study design: This is a case-only research.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jul 2022

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 16, 2022

Completed
26 days until next milestone

First Posted

Study publicly available on registry

April 11, 2022

Completed
3 months until next milestone

Study Start

First participant enrolled

July 1, 2022

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2024

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2025

Completed
Last Updated

November 29, 2023

Status Verified

November 1, 2023

Enrollment Period

2.2 years

First QC Date

March 16, 2022

Last Update Submit

November 26, 2023

Conditions

Keywords

infection controlindirect contagion transmissiondigestive endoscopy center

Outcome Measures

Primary Outcomes (1)

  • Dosage of Indirect Contact Exposure of Environmental surfaces

    A liquid of Vitamin B2 and hand sanitizer (0.12mg/mL) is marked on the hands of every patient who is scheduled in the same endoscopy work unit (usually half a day) outside the endoscopy center. Then, the doctors and nurses conduct standard EGD procedure. After this endoscopy work unit is finished, the environmental surfaces touched by the patient are sampled by the wiping method. The dosage is detected by the Fluoro Max-4® fluorophotometer (HORIBA, Japan), which is quantified as a cumulative mass (μg) over all the exposure time.

    one year

Study Arms (1)

Vitamin B2 labeled group

OTHER

A liquid of vitamin B2 and hand sanitizer (0.12mg/mL) is marked on the patients' hands outside the endoscopy center.

Other: Vitamin B2 labeling

Interventions

Using medical non-toxic fluorescent agents, VB2 solution, to mark the patient's hands before endoscopy examination.

Vitamin B2 labeled group

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • During the study period, patients who were treated in the digestive endoscopy center of Beijing Union Medical College Hospital and planned to undergo gastroscopy. Age and gender are not limited temporarily.

You may not qualify if:

  • Allergic to medical non-toxic fluorescent agent: Vitamin B2 aqueous solution.
  • Poor general condition, including severe cardiopulmonary disease, difficult to tolerate examination, and coagulation disorders.
  • Patients with contraindications to endoscopy.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Peking Union Medical College Hospital

Beijing, 100730, China

RECRUITING

Study Officials

  • Shengyu Zhang, MD

    Peking Union Medical College Hospital

    STUDY DIRECTOR
  • Yuheng Zhang, MD candidate

    Peking Union Medical College Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Shengyu Zhang, M.D.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

March 16, 2022

First Posted

April 11, 2022

Study Start

July 1, 2022

Primary Completion

September 1, 2024

Study Completion

June 1, 2025

Last Updated

November 29, 2023

Record last verified: 2023-11

Locations