Parental Project and Premature Ovarian Insufficiency

NCT05310617 | Completed

• 1 other identifier: APHP220208
• Study Type: observational
• Target: 324
• Locations: 1 country
• Sites: 1

Brief Summary

One of the main repercussions of POI is infertility. When the diagnosis of POI is announced, the question of fertility is addressed and the patient is often directed towards egg donation or adoption when she has a parental project. However, there are cases of spontaneous pregnancies after diagnosis. This study was conducted to determine the proportion of patients with POI who were able to realize a parental project after diagnosis in the long term and by what means.

Conditions

Primary Ovarian Insufficiency; Infertility

Keywords

spontaneous pregnancy; adoption; oocyte donation; parental project

Outcome Measures

Primary Outcomes (1)

• Realisation of parental project

  Determine proportion of patient who realised a parental project after the diagnosis of POI

  data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed

Secondary Outcomes (12)

• Determine how and to what extent they have carried out their parental project

  data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed

• determine how many children on average these patients had after the diagnosis of POI.

  data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed

• determine the delay between the diagnosis of POI and the birth of the first child after the diagnosis according to the method

  data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed

• Survey. Describe the characteristics of patients who were able to have a child after diagnosis

  data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed

• Survey. Describe the characteristics of patients who were able to have a child after diagnosis

  data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed

Interventions

Survey OTHER

Survey on the parental project and its realisation

Eligibility Criteria

• Age: 18 Years+
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with POI who were hospitalized in a day hospital (HDJ) in the endocrinology and reproductive medicine department of the Pitié-Salpêtrière hospital for the etiological assessment of ovarian insufficiency and its repercussions between 31/12/1982 and 12/01/2021

You may qualify if:

• Patients at least 18 years old at the time of the survey
• Patients with a diagnosis of PIO according to the current definition: cycle disturbances of more than 4 months and FSH \> 25 on 2 measurements one month apart
• Patients having been hospitalized in day hospital (HDJ) in the endocrinology and reproductive medicine department of the Pitié-Salpêtrière hospital for the etiological assessment of ovarian insufficiency and its repercussions between December 31, 1982 and January 12, 2021
• Valid contact information available: address, cell phone, e-mail
• Patients who have been informed and do not object to participate in the study

You may not qualify if:

• Turner syndrome
• POI secondary to oncology treatments (chemotherapy, pelvic radiotherapy)
• Opposition to participating in the study

Sponsors & Collaborators

• Assistance Publique - Hôpitaux de Paris: lead

Study Sites (1)

Service d'endocrinologie et médecine de la reproduction

Paris, 75013, France

Location

MeSH Terms

Conditions

Primary Ovarian Insufficiency; Infertility

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Ovarian Diseases; Adnexal Diseases; Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases; Gonadal Disorders; Endocrine System Diseases

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Philippe Touraine, Pr

  APHP

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 21, 2022
• First Posted: April 5, 2022
• Study Start: June 20, 2022
• Primary Completion: June 20, 2022
• Study Completion: June 20, 2022
• Last Updated: October 4, 2022

Record last verified: 2022-09

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)