ROX Index in Acute Respiratory Failure
Role of ROX Index as an Indicator for Non-invasive Ventilation in Acute Respiratory Failure
1 other identifier
observational
100
1 country
1
Brief Summary
evaluation of ROX index among ICU patients to evaluate the success of non invasive ventilation or the need for intubation
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Mar 2022
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 21, 2022
CompletedFirst Submitted
Initial submission to the registry
March 25, 2022
CompletedFirst Posted
Study publicly available on registry
April 4, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2024
CompletedApril 4, 2022
March 1, 2022
1 year
March 25, 2022
March 25, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
Success vs failure of non invasive ventilation
by ROX index calculation
within 6 months
Interventions
observation of ROX index to evaluate the efficacy of non invasive ventilation
Eligibility Criteria
patients administered in chest ICU in Assiut university hospital
You may qualify if:
- Participants admitted to RICU with type I and type II respiratory failure requiring NIV support with one or more of the following :
- PaO2/FiO2 less than or equal to 300 mmHg despite supplying oxygen at a flow rate ≥ to 10 l/min for ≥ 15 min
- Patients requiring ventilatory support due to increased respiratory rate ≥ 25 breaths/min or using accessory muscles of respiration
You may not qualify if:
- \. Absolute indication for intubation like coma, hemodynamic instability, or life-threatening arrhythmia.
- \. Contraindication to NIV like untreated pneumothorax, pneumothorax with air leak, widespread facial burn or trauma, tracheotomy,or active upper gastrointestinal bleeding.
- \. Resusal to participate in the study
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Assiut university
Asyut, Egypt
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 5 Days
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Kholoud Zakaria
Study Record Dates
First Submitted
March 25, 2022
First Posted
April 4, 2022
Study Start
March 21, 2022
Primary Completion
April 1, 2023
Study Completion
March 1, 2024
Last Updated
April 4, 2022
Record last verified: 2022-03