NCT05306821

Brief Summary

The primary objective is to evaluate and compare the short-term and medicum-term effectiveness of 2 types of interventions in 2 different hospitals to improve the adequacy of hospital thromboprophylaxis among acute medical inpatients.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
600

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2020

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2020

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

February 2, 2022

Completed
2 months until next milestone

First Posted

Study publicly available on registry

April 1, 2022

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2024

Completed
Last Updated

May 10, 2023

Status Verified

May 1, 2023

Enrollment Period

4.3 years

First QC Date

February 2, 2022

Last Update Submit

May 8, 2023

Conditions

Venous Thromboembolism

Outcome Measures

Primary Outcomes (1)

  • Proportion of patients with an adequate thromboprophylaxis

    90 days

Secondary Outcomes (2)

  • Incidence of venous thromboembolism

    90 days

  • Incidence of major bleeding

    90 days

Study Arms (2)

Implementation of an electronic tool for risk stratification and thromboprophylaxis prescription

EXPERIMENTAL
Other: Comprehensive electronic tool in the electronic medical chartOther: Educative sessions

Implementation of educative sessions and pocket cards for thromboprophylaxis

EXPERIMENTAL
Other: Educative sessionsOther: Pocket card

Interventions

Comprehensive electronic tool in the electronic medical chartOTHER

Use of a comprehensive electronic tool in the electronic medical chart to help the stratification of risk of VTE and the subsequent prescription of an adequate thromboprophylaxis

Implementation of an electronic tool for risk stratification and thromboprophylaxis prescription
Educative sessionsOTHER

Educative sessions on thromboprophylaxis

Implementation of an electronic tool for risk stratification and thromboprophylaxis prescriptionImplementation of educative sessions and pocket cards for thromboprophylaxis
Pocket cardOTHER

Pocket card (guide for thromboprophylaxis)

Implementation of educative sessions and pocket cards for thromboprophylaxis

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • acute medical inpatients hospitalized at the Geneva University Hospitals or the Lugano Regional Hospitals

You may not qualify if:

  • patients already on therapeutic anticoagulation
  • patients with an estimated life expectancy of \<3 months
  • pregnancy
  • patients hospitalized for COVID-19

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Geneva University Hospitals

Geneva, Switzerland

RECRUITING

Ospedale Regionale di Lugano

Lugano, Switzerland

RECRUITING

Related Publications (1)

  • Marando M, Blondon K, Darbellay Farhoumand P, Nendaz M, Grauser D, Sallet A, Tamburello A, Pons M, Righini M, Gianella P, Blondon M. Contemporary adequacy of thromboprophylaxis in acutely ill medical patients in Switzerland: a bi-centric prospective cohort. Swiss Med Wkly. 2023 Nov 1;153:40117. doi: 10.57187/smw.2023.40117.

    PMID: 37956238DERIVED

MeSH Terms

Conditions

Venous Thromboembolism

Condition Hierarchy (Ancestors)

ThromboembolismEmbolism and ThrombosisVascular DiseasesCardiovascular Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

February 2, 2022

First Posted

April 1, 2022

Study Start

September 1, 2020

Primary Completion

December 31, 2024

Study Completion

December 31, 2024

Last Updated

May 10, 2023

Record last verified: 2023-05

Locations

CH(2)