NCT05292144

Brief Summary

Multicenter, prospective, non-randomized, post-market clinical follow-up (PMCF) study to confirm and support the clinical safety and performance of Xperience Pro to meet EU Medical Device regulation (MDR) requirements in all the CONSECUTIVE patients treated with Xperience Pro .

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
46

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Oct 2022

Shorter than P25 for all trials

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 14, 2022

Completed
9 days until next milestone

First Posted

Study publicly available on registry

March 23, 2022

Completed
7 months until next milestone

Study Start

First participant enrolled

October 26, 2022

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 26, 2023

Completed
9 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 5, 2023

Completed
Last Updated

May 30, 2023

Status Verified

May 1, 2023

Enrollment Period

6 months

First QC Date

March 14, 2022

Last Update Submit

May 26, 2023

Conditions

Keywords

MDR (Medical Device Regulations)PMCF (Post-Market Clinical Follow-up)Coronary balloon dilatation catheter

Outcome Measures

Primary Outcomes (1)

  • Safety Endpoint. Freedom from Target Lesion Failure

    Freedom from TARGET LESION FAILURE (TLF), composite endpoint of cardiac death, myocardial infarction and and new Target Lesion Revascularization (TLR)

    7 days

Secondary Outcomes (8)

  • Efficacy Endpoint. Freedom from Target Lesion Failure

    7 days

  • Freedom from Balloon rupture

    During percutaneous coronary intervention (PCI)

  • Freedom from Hypotube rupture

    During PCI

  • Freedom from Complicated withdrawal

    During PCI

  • Freedom from Coronary perforation

    During PCI

  • +3 more secondary outcomes

Study Arms (1)

Coronary Artery Disease (CAD)

Device: Xperience Pro

Interventions

Patients in whom treatment with (Xperience Pro) has been attempted

Coronary Artery Disease (CAD)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients treated with Xperience pro according to routine hospital practice and following instructions for use

You may qualify if:

  • Patient treated with Xperience pro according to routine hospital practice and following instructions for use
  • Informed consent signed

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Hospital Clinic de Barcelona

Barcelona, 08036, Spain

Location

Hospital Universitario de Getafe

Getafe, 28905, Spain

Location

Hospital Universitario 12 de Octubre

Madrid, 28041, Spain

Location

Hospital Universitario Marques de Valdecilla

Santander, 39008, Spain

Location

Hospital Universitario Virgen de Valme

Seville, 41014, Spain

Location

Related Publications (3)

  • Gruntzig A. Transluminal dilatation of coronary-artery stenosis. Lancet. 1978 Feb 4;1(8058):263. doi: 10.1016/s0140-6736(78)90500-7. No abstract available.

    PMID: 74678BACKGROUND
  • Kandzari DE, Zankar AA, Teirstein PS, Brilakis ES, Banerjee S, Price MJ, Stinis CT, Hudson PA, Dahle TG, Eng M, Brown R, Ferguson A, Addo TA, Popma JJ. Clinical outcomes following predilation with a novel 1.25-mm diameter angioplasty catheter. Catheter Cardiovasc Interv. 2011 Mar 1;77(4):510-4. doi: 10.1002/ccd.22734. Epub 2010 Nov 4.

    PMID: 21351225BACKGROUND
  • Kandzari DE, Teirstein PS, Kereiakes DJ, Cannon LA, Hearne SE, Kuo HC, Ying SW, Cheong WF, Popma JJ. Procedural effectiveness of a novel 1.20 mm diameter angioplasty catheter: clinical and angiographic outcomes. J Interv Cardiol. 2013 Apr;26(2):131-6. doi: 10.1111/j.1540-8183.2013.12021.x. Epub 2013 Jan 31.

    PMID: 23369084BACKGROUND

MeSH Terms

Conditions

Coronary Artery DiseaseMyocardial Ischemia

Condition Hierarchy (Ancestors)

Coronary DiseaseHeart DiseasesCardiovascular DiseasesArteriosclerosisArterial Occlusive DiseasesVascular Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 14, 2022

First Posted

March 23, 2022

Study Start

October 26, 2022

Primary Completion

April 26, 2023

Study Completion

May 5, 2023

Last Updated

May 30, 2023

Record last verified: 2023-05

Locations