Pulsed Radiofrquency Targeting Mid Cervical Medial Branches Versus GON for Cervicogenic Headache

NCT05289414 | Completed

• 1 other identifier: PRF GON vs midcervical in CEH
• Study Type: interventional
• Target: 43
• Locations: 1 country
• Sites: 1

Brief Summary

To detect the Clinical efficacy of pulsed radiofrequency treatment targeting the mid cervical medial branches versus greater occipital nerve for cervicogenic headache

Conditions

Cervicogenic Headache

Outcome Measures

Primary Outcomes (1)

• visual analog scale (VAS)

  Assessment of pain will be done using VAS The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" and "worst pain."

  6 months

Secondary Outcomes (5)

• Visual analogue scale

  3 months

• visual analogue scale

  1 month

• visual analogue scale

  2 weeks

• visual analogue scale

  48 hours

• patient satisfactory score

  6 month

Study Arms (2)

PRF on mid cervical medial branches

ACTIVE COMPARATOR

first group of patients will be sujected to pulsed radiofrequency on mid cervical medial branches

Device: Radiofrequency on mid cervical medial branches

PRF on greater occipital nerve

ACTIVE COMPARATOR

second group of patients will be subjected to pulsed radiofrequency on Greater occipital nerve

Device: Radiofrequency

Interventions

Radiofrequency on mid cervical medial branches DEVICE

patients with diagnosis of cervicogenic headache will be subjected to radiofrequency on mid cervical medial branches

PRF on mid cervical medial branches

Radiofrequency DEVICE

patients with diagnosis of cervicogenic headache will be subjected to radiofrequency on Greater occipital nerve

PRF on greater occipital nerve

Eligibility Criteria

• Age: 18 Years - 85 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• medically stable outpatients with confirmed diagnosis of cervicogenic headache according to International Headache society
• Are reliable and willing to make themselves available for the duration of the study and are willing to follow up.
• Men or women older than 18years of age .
• clear written informed consent from each participant in the trial.

You may not qualify if:

• )presence of clinically significant medical or psychiatric condition that may increase the risk associated with the study 3)participation in any other type of medical research that may interfere with the interpretation of the study.
• )patients with haemocoagulation disorders, local infection or those who refused to consent

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Tarek

Asyut, Egypt

Location

Related Publications (4)

• Sjaastad O, Bakketeig LS. Prevalence of cervicogenic headache: Vaga study of headache epidemiology. Acta Neurol Scand. 2008 Mar;117(3):173-80. doi: 10.1111/j.1600-0404.2007.00962.x. Epub 2007 Nov 20.

  PMID: 18031563 BACKGROUND

• Chua NH, Vissers KC, Sluijter ME. Pulsed radiofrequency treatment in interventional pain management: mechanisms and potential indications-a review. Acta Neurochir (Wien). 2011 Apr;153(4):763-71. doi: 10.1007/s00701-010-0881-5. Epub 2010 Nov 30.

  PMID: 21116663 BACKGROUND

• Hamer JF, Purath TA. Response of cervicogenic headaches and occipital neuralgia to radiofrequency ablation of the C2 dorsal root ganglion and/or third occipital nerve. Headache. 2014 Mar;54(3):500-10. doi: 10.1111/head.12295. Epub 2014 Jan 16.

  PMID: 24433241 BACKGROUND

• Palea O, Andar HM, Lugo R, Granville M, Jacobson RE. Direct Posterior Bipolar Cervical Facet Radiofrequency Rhizotomy: A Simpler and Safer Approach to Denervate the Facet Capsule. Cureus. 2018 Mar 14;10(3):e2322. doi: 10.7759/cureus.2322.

  PMID: 29765790 BACKGROUND

MeSH Terms

Conditions

Post-Traumatic Headache

Condition Hierarchy (Ancestors)

Headache Disorders, Secondary; Headache Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Masking Details: triple blind study (participant ,investigator and outcome assessor) will be masked and will not konw what is the type of treatment patients receive
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Model Details: two groups of patients diagnosed with cervicogenic headache Will be randomly subjected to either RF on greater occipital nerve or mid cervical medial branches

Study Record Dates

• First Submitted: March 13, 2022
• First Posted: March 21, 2022
• Study Start: September 1, 2022
• Primary Completion: November 1, 2024
• Study Completion: December 31, 2024
• Last Updated: March 7, 2025

Record last verified: 2025-03

Locations

EG (1)