Ulnar Nerve Neurotization After Ulnar Nerve Injury

NCT05283785 | Unknown

• 1 other identifier: ulnar nerve neurotization
• Study Type: observational
• Target: 22
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study will evaluate the hand intrinsic muscles functional recovery after distal neurotization of ulnar nerve

Conditions

Ulnar Nerve Injury

Outcome Measures

Primary Outcomes (1)

• evaluate the hand intrinsic muscles functional recovery after distal neurotization of ulnar nerve

  (1) Evaluation of hand intrinsic muscle functional recovery by : A- Muscle power by standard Medical Research Council (MRC) grading B- grip strength by dynamometer C- pinch strength will done based on grading of adductor pollicis muscle. D- Evaluation of clawing will done based on clinical observation E- DASH( Disabilities of the Arm, Shoulder and Hand ) score pre and post

  8 months

Study Arms (2)

( group 1)

End to End sutures

Procedure: End To End or End to side sutures

( group 2 )

End to Side sutures

Procedure: End To End or End to side sutures

Interventions

End To End or End to side sutures PROCEDURE

End to end or End to side sutures of ulnar nerve by nerve to quadratus muscle ( branch of anterior interosseous nerve )

( group 1); ( group 2 )

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

1. test adductor pollicis muscle. 2. test palmar inter-osseii. 3. test dorsal inter-osseii. 4. test lumbricals. * Investigations: * Radiological: * Plain X-ray * EMG and nerve conduction velocity * Laboratory : Full laboratory investigations Steps of action and techniques used: Pre-operative preparation: 1. recording of pre-existing muscle power, 2. Clarifying of realistic goals before the surgery, 3. anti-biotic within 1 hour before surgery\> . Surgical techniques transfer of the motor branch of the anterior interosseous nerve that supply pronator quadrates muscle to the motor division of the ulnar nerve ( the deep branch of the ulnar nerve ) by end to end or end to side suture

You may qualify if:

• Site of the injury: at or proximal to level of the elbow
• Nature of the injury; post traumatic injury.
• Sex; both males and females.
• Age; any age.
• Time of presentation of injury: less than 6 months from injury.

You may not qualify if:

• Any patient with non-post traumatic injury either inflammatory or tumor caused palsy or idiopathic.
• Any distal injury below origin of FCU branch.
• Delayed presentation after 6 months of injury.
• Any patient refusing participation in this study.

Sponsors & Collaborators

• Assiut University: lead

Study Officials

• Amr El-Sayed A Ibrahim, Prof Dr

  Orthopedic and Microsurgery department , assiut university hospital

  STUDY DIRECTOR

• Yasser M Farouk Ragheb, Lecturar

  Orthopedic and Microsurgery department , assiut university hospital

  STUDY DIRECTOR

Central Study Contacts

Mario S Shawkey Basilios, resident

CONTACT

01007936606; Mariobasilios492@gmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Target Duration: 8 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident doctor at orthopedic department , assuit university hospital

Study Record Dates

• First Submitted: March 2, 2022
• First Posted: March 17, 2022
• Study Start: October 1, 2022
• Primary Completion: October 1, 2024
• Study Completion: December 1, 2024
• Last Updated: March 31, 2022

Record last verified: 2022-03