NCT05278442

Brief Summary

Evaluation of the Accuracy and Safety of the LaserArcs Femtosecond Cataract Surgery Arcuate Incision Nomogram in Patients Undergoing Cataract Surgery and Astigmatism Reduction

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Apr 2022

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 3, 2022

Completed
1 month until next milestone

First Posted

Study publicly available on registry

March 14, 2022

Completed
18 days until next milestone

Study Start

First participant enrolled

April 1, 2022

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 7, 2022

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 8, 2022

Completed
Last Updated

November 1, 2022

Status Verified

October 1, 2022

Enrollment Period

4 months

First QC Date

February 3, 2022

Last Update Submit

October 28, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Primary Endpoint -Postoperative magnitude of manifest astigmatism (diopters) divided by preoperative magnitude of manifest astigmatism (diopters)

    Percent change in absolute magnitude of astigmatism

    Up to 3 months

Secondary Outcomes (2)

  • Mean Attempted vs Achieved Correction (see description)

    Up to 3 months

  • Secondary Endpoint - Standard deviation of attempted vs achieved correction = standard deviation of of all individual calculated values for attempted vs achieved correction

    Up to 3 months

Other Outcomes (1)

  • Exploratory Endpoint - Postoperative manifest refraction cylinder and axis is the measured magnitude of spherical and cylindrical refraction at the postoperative visit.

    Up to 3 months

Interventions

LaserArcs.com is an online arcuate incision nomogram calculator initially developed on the basis of 12 months of data tabulation of patients undergoing femtosecond surgery with arcuate incisions

Eligibility Criteria

Age22 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The study aims to enroll 50 patients that had previous cataract surgery performed with femtosecond lasers.

You may qualify if:

  • Patients with cataract and otherwise healthy eyes, not exhibiting any significant ocular morbidity that would be expected to influence outcome measures.
  • Patients who are 22 years of age or older
  • Patients whose preoperative astigmatism was greater than 0.5 D
  • Patients who were implanted with a non-toric IOL.
  • Patients whose laser astigmatic keratotomy was planned using the LASER arcs nomogram

You may not qualify if:

  • Patients with visually significant co-morbidities (corneal, retina, optic nerve disease) that could affect their satisfaction with surgery
  • Patients with surgical complications either during or after surgery (capsule tears, iris trauma, decentered IOL, cystoid macular edema, etc.) that would, in the judgment of the investigator, influence the outcome measures of the study.
  • Patients with previous refractive surgery within the past 6 months prior to cataract surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Quantum Vision Centers

Belleville, Illinois, 62226, United States

Location

MeSH Terms

Conditions

CataractAstigmatism

Condition Hierarchy (Ancestors)

Lens DiseasesEye DiseasesRefractive Errors

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 3, 2022

First Posted

March 14, 2022

Study Start

April 1, 2022

Primary Completion

August 7, 2022

Study Completion

August 8, 2022

Last Updated

November 1, 2022

Record last verified: 2022-10

Locations