Asia Glaucoma Registry

NCT05278299 | Unknown DMC

• 1 other identifier: UW 21-664
• Study Type: observational
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

Glaucoma remains a leading cause for irreversible visual impairment and blindness worldwide and it disproportionately affects people residing in Asia, there is a need to ensure optimal management of the disease in patients with glaucoma. The ability to estimate the rates of structural and functional loss in patients with glaucoma will enable clinicians to identify those with rapidly deteriorating conditions or those at-risk, and to therefore provide timely treatment to these patients. Despite this, there are currently several challenges in identifying rapid-progressors in glaucoma, including lack of consensus on the definition of 'rapid' progression and what rates of change of visual field (VF) encompass clinically significant deterioration relevant to the patients. As such, the Asia Glaucoma Registry is intended to collect data to advance the understanding of glaucoma and its progression in Asia and to understand the management patterns of glaucoma in Asia. The Registry will also provide research data for future collaborative scientific research projects.

Conditions

POAG

Outcome Measures

Primary Outcomes (1)

• The proportion of fast progressors among patients with POAG or PACG and the risk factors for fast progression

  1 year

Secondary Outcomes (1)

• The severity and spectrum of glaucoma in different ethnic groups in Asia and the practice patterns of glaucoma management in Asia

  1 year

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

A sample size calculation will be conducted to determine the minimum number of subjects to be included in the full-scaled study. Both eyes of patients will be included if both eyes are eligible for inclusion.

You may qualify if:

• Patients with a diagnosis of POAG or PACG
• Age ≥18 years at diagnosis.

You may not qualify if:

• Secondary causes of glaucoma (e.g. uveitic glaucoma, neovascular glaucoma, traumatic glaucoma, exfoliative glaucoma, pigmentary glaucoma, phacomorphic glaucoma, malignant glaucoma)
• Any neurological disease that may result in VF loss (e.g. stroke)
• History of optic neuropathy other than glaucoma (including those related to thyroid eye disease);
• Prior retinal surgery.

Sponsors & Collaborators

• The University of Hong Kong: lead

Study Sites (1)

Leung Kai Shun

Hong Kong, Hong Kong

Location

Study Officials

• Kai Shun, Christopher Leung

  The University of Hong Kong

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Head and Clinical Professor

Study Record Dates

• First Submitted: March 3, 2022
• First Posted: March 14, 2022
• Study Start: October 1, 2021
• Primary Completion: September 30, 2022
• Study Completion: September 30, 2023
• Last Updated: March 14, 2022

Record last verified: 2022-03

Data Sharing

• IPD Sharing: Will not share

Locations

HK (1)