NCT05275764

Brief Summary

Approximately 30 eyes with congenital cataract who underwent primary or secondary intraocular lens implantation surgery at Zhejiang Eye Hospital from March 2018 to December 2020 were enrolled. According to the implantation method of IOL, patients were devided into the optic capture group and the endocapsular group. And through the clinical parameters of postoperative best corrected visual acuity (BCVA), intraocular pressure (IOP), IOL position and whether appear visual axis opacity to compare the outcome of the 2 IOL implantation methods.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Nov 2021

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2021

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

February 19, 2022

Completed
20 days until next milestone

First Posted

Study publicly available on registry

March 11, 2022

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2022

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2022

Completed
Last Updated

March 11, 2022

Status Verified

March 1, 2022

Enrollment Period

8 months

First QC Date

February 19, 2022

Last Update Submit

March 10, 2022

Conditions

Outcome Measures

Primary Outcomes (2)

  • IOL position

    The horizontal and vertical inclination of IOL

    through study completion, an average of 1 year

  • BCVA

    best corrected visual acuity

    through study completion, an average of 1 year

Study Arms (2)

optic capture group

IOL optic was captured through the posterior continuous curvilinear capsulorhexis

Procedure: primary or secondary intraocular lens implantation surgery

endocapsular group

IOL was placed in the bag

Procedure: primary or secondary intraocular lens implantation surgery

Interventions

primary or secondary intraocular lens implantation surgery

endocapsular groupoptic capture group

Eligibility Criteria

Age1 Year - 10 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodProbability Sample
Study Population

Children with congenital cataracts who underwent primary or secondary intraocular lens implantation surgery at the Eye Hospital Affiliated to Wenzhou Medical University.

You may qualify if:

  • Children aged 1 to 10 years diagnosed with congenital cataract
  • underwent I / II IOL implantation in our hospital
  • corneal diameter more than 9mm
  • Good compliance

You may not qualify if:

  • Patients with other ocular or systemic diseases
  • patients whose IOL cannot be implanted in or after the capsule due to ocular conditions
  • Children with a history of other ocular surgery
  • Low compliance

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Eye Hospital of Wenzhou Medical College

Wenzhou, Zhejiang, 325027, China

RECRUITING

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Vice president of Eye Hospital of Wenzhou Medical University

Study Record Dates

First Submitted

February 19, 2022

First Posted

March 11, 2022

Study Start

November 1, 2021

Primary Completion

June 30, 2022

Study Completion

December 31, 2022

Last Updated

March 11, 2022

Record last verified: 2022-03

Data Sharing

IPD Sharing
Will not share

Locations