Veterans Coordinated Community Care (3C) Study
3C
Targeted Intensive Case Management of Veterans at Risk of Suicide Post Inpatient Hospitalization
1 other identifier
interventional
850
1 country
7
Brief Summary
Veterans Coordinated Community Care (3C) Study will recruit 850 Veterans at risk for suicide post inpatient hospitalization. Each participant will be randomly assigned to treatment as usual (TAU) or TAU plus the Coping Long Term with Active Suicide Program (CLASP), with follow-up for 6 months after discharge. Outcomes include suicide-related behaviors (including deaths due to suicide, opioid overdose, or other substance-related accidents; and nonfatal suicide attempts) and suicidal ideation and functioning.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Jan 2022
Longer than P75 for not_applicable
7 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 11, 2022
CompletedFirst Submitted
Initial submission to the registry
January 27, 2022
CompletedFirst Posted
Study publicly available on registry
March 9, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 30, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
June 30, 2026
January 14, 2026
January 1, 2026
4.5 years
January 27, 2022
January 13, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Veterans Affairs Healthcare System (VAHS) health and administrative records on suicide related behaviors
Suicide related behaviors that include deaths due to suicide, opioid overdose, or other substance-related accidents; and nonfatal suicide attempts.
6 months after discharge
3C Suicide Outcome Measure
Study specific aggregate measure (3C Suicide Outcome Measure) containing selected items from the Columbia-Suicide Severity Rating Scale (C-SSRS), Self-Injurious Thoughts and Behaviors Interview (SITBI), and Suicidal Behaviors Questionnaire (SBQ).
6 months after discharge
Secondary Outcomes (2)
Veterans Affairs Healthcare System (VAHS) health and administrative records on suicidal ideation and functioning
6 months after discharge
3C Suicidal Ideation and Functioning Outcome Measure
6 months after discharge
Study Arms (2)
Coping Long Term with Active Suicide Program (CLASP)
EXPERIMENTALThe CLASP intervention is an adjunctive, telehealth-based behavioral intervention designed to reduce suicidal behavior among individuals at high risk for suicide going through periods of transition. CLASP is designed to intervene on four risk factor targets: ongoing treatment engagement, problem-solving, social and family support, and hopelessness. In addition to these general factors, the CLASP provider also has the flexibility to identify and target certain "patient-specific" risk factors (e.g., substance misuse) for intervention. CLASP will begin after completion of the baseline assessment, and will continue for 6 months post-discharge. CLASP will be comprised of: a) 3 initial sessions while participants are still inpatients (can occur post-discharge if needed); b) 12 brief telehealth sessions over 6-months post-discharge; c) 6 brief SO telehealth sessions.
Treatment As Usual (TAU)
NO INTERVENTIONTreatment As Usual (TAU) consists of unrestricted treatment provided as part of routine care in the Veterans Health Administration (VHA) following inpatient hospitalization. Study staff will provide no additional treatment in this arm.
Interventions
Telehealth-based case management intervention designed to reduce suicidal behavior among individuals at high risk for suicide across the transition from inpatient hospitalization to the community.
Eligibility Criteria
You may qualify if:
- Inpatient Veteran at high-risk for post-discharge suicide (as flagged by the study's validated prediction model)
- years or older
- Access to a telephone after discharge.
You may not qualify if:
- Impaired decision-making capacity
- Limited or no English language proficiency
- Terminal illness
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Brown Universitylead
- Harvard Universitycollaborator
- Canandaigua VA Medical Centercollaborator
- West Virginia Universitycollaborator
- The Warren Alpert Foundationcollaborator
Study Sites (7)
Central Arkansas Veterans Healthcare System
Little Rock, Arkansas, 72205, United States
VA Boston Healthcare System
Boston, Massachusetts, 02301, United States
Minneapolis VA Health Care System
Minneapolis, Minnesota, 55417, United States
VA St. Louis Health Care System
St Louis, Missouri, 63125, United States
VA Pittsburgh Healthcare System
Pittsburgh, Pennsylvania, 15240, United States
VA Tennessee Valley Health Care System
Murfreesboro, Tennessee, 37129, United States
VA North Texas Healthcare System
Dallas, Texas, 75216, United States
Related Publications (4)
Miller IW, Gaudiano BA, Weinstock LM. The Coping Long Term with Active Suicide Program: Description and Pilot Data. Suicide Life Threat Behav. 2016 Dec;46(6):752-761. doi: 10.1111/sltb.12247. Epub 2016 Apr 2.
PMID: 27038050BACKGROUNDKessler RC, Bauer MS, Bishop TM, Demler OV, Dobscha SK, Gildea SM, Goulet JL, Karras E, Kreyenbuhl J, Landes SJ, Liu H, Luedtke AR, Mair P, McAuliffe WHB, Nock M, Petukhova M, Pigeon WR, Sampson NA, Smoller JW, Weinstock LM, Bossarte RM. Using Administrative Data to Predict Suicide After Psychiatric Hospitalization in the Veterans Health Administration System. Front Psychiatry. 2020 May 6;11:390. doi: 10.3389/fpsyt.2020.00390. eCollection 2020.
PMID: 32435212BACKGROUNDMiller IW, Camargo CA Jr, Arias SA, Sullivan AF, Allen MH, Goldstein AB, Manton AP, Espinola JA, Jones R, Hasegawa K, Boudreaux ED; ED-SAFE Investigators. Suicide Prevention in an Emergency Department Population: The ED-SAFE Study. JAMA Psychiatry. 2017 Jun 1;74(6):563-570. doi: 10.1001/jamapsychiatry.2017.0678.
PMID: 28456130BACKGROUNDWeinstock LM, Bishop TM, Bauer MS, Benware J, Bossarte RM, Bradley J, Dobscha SK, Gibbs J, Gildea SM, Graves H, Haas G, House S, Kennedy CJ, Landes SJ, Liu H, Luedtke A, Marx BP, Miller A, Nock MK, Owen RR, Pigeon WR, Sampson NA, Santiago-Colon A, Shivakumar G, Urosevic S, Kessler RC. Design of a multicenter randomized controlled trial of a post-discharge suicide prevention intervention for high-risk psychiatric inpatients: The Veterans Coordinated Community Care Study. Int J Methods Psychiatr Res. 2024 Dec;33(4):e70003. doi: 10.1002/mpr.70003.
PMID: 39352173DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Lauren Weinstock, PhD
Brown University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
January 27, 2022
First Posted
March 9, 2022
Study Start
January 11, 2022
Primary Completion (Estimated)
June 30, 2026
Study Completion (Estimated)
June 30, 2026
Last Updated
January 14, 2026
Record last verified: 2026-01
Data Sharing
- IPD Sharing
- Will share
- Time Frame
- De-identified data will become available after the study has ended.
- Access Criteria
- De-identified data are made available to users at ICPSR member institutions.
De-identified study data will be made available through the Inter-university Consortium for Political and Social Research (ICPSR) after the study has ended.