NCT05270577

Brief Summary

To compare prehabilitation with physical exercise, psychological support, nutritional support and smoke/alchol stop to "standard of care" before canceer surgery.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
90

participants targeted

Target at P50-P75 for not_applicable cancer

Timeline
Completed

Started Mar 2022

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 16, 2022

Completed
13 days until next milestone

Study Start

First participant enrolled

March 1, 2022

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 8, 2022

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2023

Completed
Last Updated

March 8, 2022

Status Verified

February 1, 2022

Enrollment Period

1.8 years

First QC Date

February 16, 2022

Last Update Submit

February 26, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • 6 minute walk test (6mwt)

    6 minute walk test (6mwt)

    12 weeks

Secondary Outcomes (22)

  • 30 s chair stand test

    12 weeks

  • Test of hand grip strength

    12 weeks

  • International Physical Activity Questionnaire

    12 weeks

  • Cardiopulmonary exercise test with ventilatory gas analysis

    12 weeks

  • The presence of malnutrition evaluated with the Global Leadership Initiative on Malnutrition (GLM) criteria

    12 weeks

  • +17 more secondary outcomes

Study Arms (2)

Prehabilitation

EXPERIMENTAL

Prehabilitation with physical exercise, psychological support, nutritional support and smoking/alchohol stop

Other: Prehabilitation

Standard care

ACTIVE COMPARATOR

Standard preoperative recomendations

Other: Standard care

Interventions

prehabilitation

Prehabilitation

No intervention

Standard care

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients, aged 18 or older, who have been evaluated as eligible for surgery for malignancy in the esophagus, rectum or liver (only metastases from colorectal cancer) will be evaluated for participation.

You may not qualify if:

  • Surgery is scheduled in less than 12 weeks.
  • Paralytic or completely immobilized patient, condition making physical training impractical.
  • Cognitive disability making participation impossible.
  • Not speaking or understanding the Swedish language well enough to read and understand the informed consent form.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Neoplasms

Interventions

Preoperative ExerciseStandard of Care

Intervention Hierarchy (Ancestors)

Perioperative CarePatient CareTherapeuticsSurgical Procedures, OperativeExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological PhenomenaHealth ServicesHealth Care Facilities Workforce and ServicesQuality Indicators, Health CareQuality of Health CareHealth Services AdministrationHealth Care Quality, Access, and Evaluation

Study Officials

  • Bergthor Björnsson, MD, PhD

    Linkoeping University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Bergthor Björnsson, MD, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: Randomized controlled trial
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

February 16, 2022

First Posted

March 8, 2022

Study Start

March 1, 2022

Primary Completion

December 1, 2023

Study Completion

December 1, 2023

Last Updated

March 8, 2022

Record last verified: 2022-02

Data Sharing

IPD Sharing
Will not share