Effects of Brachial Plexus Block on Tissue Oxygenation

NCT05269251 | Completed

• 1 other identifier: 357
• Study Type: observational
• Target: 99
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to measure the effects of sympathetic blockade caused by peripheral nerve blocks performed with the axillary, infraclavicular and interscalene approach on tissue oxygenation with Near Infrared Spectroscopy (NIRS), to evaluate and compare the radial artery flow velocity and diameter in the blocked extremity, and to investigate whether there is a relationship with the quality of the sensory and motor block.

Conditions

Tissue Oxygenation

Outcome Measures

Primary Outcomes (1)

• tissue oxygenation

  Measured from both extremities by Near Infrared Spectroscopy for 30 min after brachial nerve block.

  30 minutes

Secondary Outcomes (1)

• Radial artery diameter

  30 minutes

Study Arms (3)

Axillary Brachial Plexus Block

Our study includes 3 groups, 33 patients each who underwent axillary, infraclavicular and interscalene blocks. In the study, which of the axillary, infraclavicular and interscalene blocks will be preferred, will be decided by an experienced anesthesiologist in accordance with the type of surgery to be performed. Demographic data, comorbidities, and smoking will be questioned in each group, arterial blood pressure, heart rate, body temperature, radial artery diameter and flow velocities will be recorded before peripheral nerve block is applied, and tissue oxygenation will be measured with Near Infrared Spectroscopy (NIRS) in the extremities with and without block. Tissue oxygenation, radial artery flow velocity and diameters, body temperature will be measured simultaneously at 0(basal)-5-10-15-20-25 and 30th minutes after the application of the block. test will be applied and the success of the procedure will be determined accordingly.

Device: Near Infrared Spectroscopy (NIRS)

Infraclavicular Brachial Plexus Block

Our study includes 3 groups, 33 patients each who underwent axillary, infraclavicular and interscalene blocks. In the study, which of the axillary, infraclavicular and interscalene blocks will be preferred, will be decided by an experienced anesthesiologist in accordance with the type of surgery to be performed. Demographic data, comorbidities, and smoking will be questioned in each group, arterial blood pressure, heart rate, body temperature, radial artery diameter and flow velocities will be recorded before peripheral nerve block is applied, and tissue oxygenation will be measured with Near Infrared Spectroscopy (NIRS) in the extremities with and without block. Tissue oxygenation, radial artery flow velocity and diameters, body temperature will be measured simultaneously at 0(basal)-5-10-15-20-25 and 30th minutes after the application of the block. test will be applied and the success of the procedure will be determined accordingly.

Device: Near Infrared Spectroscopy (NIRS)

Interscalene Brachial Plexus Block

Our study includes 3 groups, 33 patients each who underwent axillary, infraclavicular and interscalene blocks. In the study, which of the axillary, infraclavicular and interscalene blocks will be preferred, will be decided by an experienced anesthesiologist in accordance with the type of surgery to be performed. Demographic data, comorbidities, and smoking will be questioned in each group, arterial blood pressure, heart rate, body temperature, radial artery diameter and flow velocities will be recorded before peripheral nerve block is applied, and tissue oxygenation will be measured with Near Infrared Spectroscopy (NIRS) in the extremities with and without block. Tissue oxygenation, radial artery flow velocity and diameters, body temperature will be measured simultaneously at 0(basal)-5-10-15-20-25 and 30th minutes after the application of the block. test will be applied and the success of the procedure will be determined accordingly.

Device: Near Infrared Spectroscopy (NIRS)

Interventions

Near Infrared Spectroscopy (NIRS) DEVICE

After the brachial plexus block, the regional oxygen saturation (rSO2) was monitored for 30 minutes with the Regional Oximetry System (O3™, Masimo, Irvine, CA) and the radial artery diameter with ultrasound in the same period.

Also known as: Regional Oximetry System (O3™, Masimo, Irvine, CA)

Axillary Brachial Plexus Block; Infraclavicular Brachial Plexus Block; Interscalene Brachial Plexus Block

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

ASA I-III patients aged 18-65 years, who were decided to apply axillary,infraclavicular and interscalene blocks as the anesthesia method, will be included in the study.

You may qualify if:

• ASA I-III patients
• Patients between the ages of 18 and 65
• Patients who applied axillary block
• Patients who applied infraclavicular block
• Patients who applied interscalene block

You may not qualify if:

• Peripheral nerve disease a history
• History of thrombosis in the extremity to be blocked
• History of embolism in the extremity to be blocked
• Presence of neuropathy

Sponsors & Collaborators

• Gazi University: lead

Study Sites (1)

Demet Coskun

Ankara, Turkey (Türkiye)

Location

MeSH Terms

Interventions

Spectroscopy, Near-Infrared

Intervention Hierarchy (Ancestors)

Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis; Spectrum Analysis; Chemistry Techniques, Analytical; Investigative Techniques

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Target Duration: 10 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor M.D

Study Record Dates

• First Submitted: February 25, 2022
• First Posted: March 7, 2022
• Study Start: April 12, 2021
• Primary Completion: May 31, 2022
• Study Completion: August 1, 2022
• Last Updated: March 1, 2024

Record last verified: 2024-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)