Effect of Cranberry Extract on the Urinary System

NCT05260554 | Completed FDA Drug

• 1 other identifier: Kırklareli University
• Study Type: observational
• Target: 2
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, we will try to emphasize the effects of using cranberry tablets, which is an alternative to antibiotic therapy, during uncomplicated urinary tract infections (only urinary tract, bladder and kidney infections did not).

Conditions

Urinary Tract Disease; Cystitis; Antibiotic Reaction

Keywords

Urinary Tract Disease; Cranberry extract; Antibiotic; Cystitis

Outcome Measures

Primary Outcomes (1)

• Treatment time

  After 7 days of treatment, the 2 treatment options were compared with each other.

  7 days

Study Arms (2)

using fosfomycin

The patients in this group; have been prescribed fosfomycin for 7 days (3 doses, two days apart).

Drug: Fosfomycin

using cranberry extract

The patients in this group; took 7 days (1 tablet each day) of cranberry tablets.

Dietary Supplement: Cranberry

Interventions

Fosfomycin DRUG

In this group with urinary tract inflammation; Fosfomycin was prescribed for 7 days (3 doses, 2 days apart). There are 80 patients in total.

Also known as: monurol

using fosfomycin

Cranberry DIETARY_SUPPLEMENT

In this group with urinary tract inflammation; 7 days (used every day) cranberry tablet was given. There are 80 patients in total.

using cranberry extract

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Among the patients who were eligible criteria, the study was terminated when the number of patients in both groups reached 80.

You may qualify if:

• Older than 18
• who have urinary tract inflammation
• who haven't kidney dissease previous

You may not qualify if:

• Younger than 18
• Who have kidney inflammation
• Pregnant patients
• Who have blood test abnormal (WBC, Ure, Creatin, CRP high level)

Sponsors & Collaborators

• Kırklareli University: lead

Study Sites (1)

Oya Guven, MD

Kırklareli, Center, 39000, Turkey (Türkiye)

Location

Related Publications (1)

• Gray M. Are cranberry juice or cranberry products effective in the prevention or management of urinary tract infection? J Wound Ostomy Continence Nurs. 2002 May;29(3):122-6. doi: 10.1067/mjw.2002.124016. No abstract available.

  PMID: 12011903 RESULT

MeSH Terms

Conditions

Urologic Diseases; Cystitis

Interventions

Fosfomycin

Condition Hierarchy (Ancestors)

Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Urinary Bladder Diseases

Intervention Hierarchy (Ancestors)

Organophosphonates; Organophosphorus Compounds; Organic Chemicals

Study Officials

• Oya Guven

  Kırklareli University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: February 18, 2022
• First Posted: March 2, 2022
• Study Start: January 26, 2022
• Primary Completion: February 18, 2022
• Study Completion: February 18, 2022
• Last Updated: March 2, 2022

Record last verified: 2022-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)