Energy Availability in Male Athletes Across the Season

NCT05259969 | Unknown

• 1 other identifier: EAMAS
• Study Type: observational
• Target: 25
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of proposed cohort observational study is assessing the risk of low energy availability and relative energy deficiency in sport in competitive adult male athletes. The changes in athlete's energy availability, health biomarkers in blood, gut microbiota composition and performance will be determined in 3 key stages across the season: during preparation, competition and transition period in a subset of athletes. The study is investigating following specific aims in the cohort of male competitive athletes: Correlation between energy availability and resting metabolic rate and metabolic functions across the season. Correlation between energy availability and reproductive functions across the season. Correlation between energy availability and hematological biomarkers across the season. Correlation between energy availability and gut microbiota composition across the season. Correlation between energy availability and performance across the season.

Conditions

Relative Energy Deficiency in Sport

Keywords

athlete; energy availability; nutrition; eating disorder

Outcome Measures

Primary Outcomes (1)

• Change in energy availability among different periods of a season

  Energy intake (kcal/day), energy expenditure (kcal/day) and fat free mass (FFM; kg) will be combined to report energy availability (kcal/kg FFM/day).

  Through study completion, an average of 1 year.

Secondary Outcomes (17)

• Change in resting metabolic rate among different periods of a season

  Through study completion, an average of 1 year.

• Change in body mass among different periods of a season

  Through study completion, an average of 1 year.

• Change in fat free body mass among different periods of a season

  Through study completion, an average of 1 year.

• Change in percentage of body fat among different periods of a season

  Through study completion, an average of 1 year.

• Change in iron status markers among different periods of a season

  Through study completion, an average of 1 year.

Other Outcomes (3)

• Change in lipid profile among different periods of a season

  Through study completion, an average of 1 year.

• Change in leptin concentration among different periods of a season

  Through study completion, an average of 1 year.

• Change in insulin-like growth factor 1 concentration among different periods of a season

  Through study completion, an average of 1 year.

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: male
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Olympic Committee of Slovenia recognized (categorized) competitive adult male athletes

You may qualify if:

• National Sport Organization identified competitive female or male athlete
• Male athlete actively training for and racing in an Olympic sports event
• Age 18-40 years

You may not qualify if:

• Under 15 years old, older than 40 years
• Female
• Para-athlete
• Non active due to illness or injury

Sponsors & Collaborators

• University of Primorska: lead

Related Publications (11)

• Areta JL, Taylor HL, Koehler K. Low energy availability: history, definition and evidence of its endocrine, metabolic and physiological effects in prospective studies in females and males. Eur J Appl Physiol. 2021 Jan;121(1):1-21. doi: 10.1007/s00421-020-04516-0. Epub 2020 Oct 23.

  PMID: 33095376 BACKGROUND

• Burke LM, Lundy B, Fahrenholtz IL, Melin AK. Pitfalls of Conducting and Interpreting Estimates of Energy Availability in Free-Living Athletes. Int J Sport Nutr Exerc Metab. 2018 Jul 1;28(4):350-363. doi: 10.1123/ijsnem.2018-0142. Epub 2018 Jul 20.

  PMID: 30029584 BACKGROUND

• Mountjoy M, Sundgot-Borgen JK, Burke LM, Ackerman KE, Blauwet C, Constantini N, Lebrun C, Lundy B, Melin AK, Meyer NL, Sherman RT, Tenforde AS, Klungland Torstveit M, Budgett R. IOC consensus statement on relative energy deficiency in sport (RED-S): 2018 update. Br J Sports Med. 2018 Jun;52(11):687-697. doi: 10.1136/bjsports-2018-099193. No abstract available.

  PMID: 29773536 BACKGROUND

• Sim A, Burns SF. Review: questionnaires as measures for low energy availability (LEA) and relative energy deficiency in sport (RED-S) in athletes. J Eat Disord. 2021 Mar 31;9(1):41. doi: 10.1186/s40337-021-00396-7.

  PMID: 33789771 BACKGROUND

• Reed JL, De Souza MJ, Williams NI. Changes in energy availability across the season in Division I female soccer players. J Sports Sci. 2013;31(3):314-24. doi: 10.1080/02640414.2012.733019. Epub 2012 Oct 18.

  PMID: 23075047 BACKGROUND

• Staal S, Sjodin A, Fahrenholtz I, Bonnesen K, Melin AK. Low RMRratio as a Surrogate Marker for Energy Deficiency, the Choice of Predictive Equation Vital for Correctly Identifying Male and Female Ballet Dancers at Risk. Int J Sport Nutr Exerc Metab. 2018 Jul 1;28(4):412-418. doi: 10.1123/ijsnem.2017-0327. Epub 2018 Jun 22.

  PMID: 29405782 BACKGROUND

• Zabriskie HA, Currier BS, Harty PS, Stecker RA, Jagim AR, Kerksick CM. Energy Status and Body Composition Across a Collegiate Women's Lacrosse Season. Nutrients. 2019 Feb 23;11(2):470. doi: 10.3390/nu11020470.

  PMID: 30813399 BACKGROUND

• Melin AK, Heikura IA, Tenforde A, Mountjoy M. Energy Availability in Athletics: Health, Performance, and Physique. Int J Sport Nutr Exerc Metab. 2019 Mar 1;29(2):152-164. doi: 10.1123/ijsnem.2018-0201. Epub 2019 Feb 26.

  PMID: 30632422 BACKGROUND

• Logue DM, Madigan SM, Melin A, Delahunt E, Heinen M, Donnell SM, Corish CA. Low Energy Availability in Athletes 2020: An Updated Narrative Review of Prevalence, Risk, Within-Day Energy Balance, Knowledge, and Impact on Sports Performance. Nutrients. 2020 Mar 20;12(3):835. doi: 10.3390/nu12030835.

  PMID: 32245088 BACKGROUND

• Loucks AB, Kiens B, Wright HH. Energy availability in athletes. J Sports Sci. 2011;29 Suppl 1:S7-15. doi: 10.1080/02640414.2011.588958. Epub 2011 Jul 28.

  PMID: 21793767 BACKGROUND

• Mountjoy M, Sundgot-Borgen J, Burke L, Carter S, Constantini N, Lebrun C, Meyer N, Sherman R, Steffen K, Budgett R, Ljungqvist A, Ackerman K. The IOC relative energy deficiency in sport clinical assessment tool (RED-S CAT). Br J Sports Med. 2015 Nov;49(21):1354. No abstract available.

  PMID: 26764434 BACKGROUND

Biospecimen

Retention: SAMPLES WITH DNA

Whole Blood, Serum, Plasma, Stool samples

MeSH Terms

Conditions

Relative Energy Deficiency in Sport; Feeding and Eating Disorders

Condition Hierarchy (Ancestors)

Mental Disorders; Signs and Symptoms, Digestive; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Nina Mohorko, PhD

  University of Primorska, Faculty of Health Sciences

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Nina Mohorko, PhD

CONTACT

+386 5 66 35 801; nina.mohorko@fvz.upr.si

Vesna Simič, MSc

CONTACT

vesna.simic@psih-klinika.si

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: January 17, 2022
• First Posted: March 2, 2022
• Study Start: May 1, 2022
• Primary Completion: September 30, 2023
• Study Completion: April 30, 2024
• Last Updated: April 11, 2022

Record last verified: 2022-04