TEAMS-BP (The Enhancement of Social Networks to Augment Management of Stroke-Blood Pressure)

NCT05258890 | Terminated Results

• 2 other identifiers: 2022P0004445P30AG064199-03
• Study Type: interventional
• Target: 64
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to compare the efficacy of a social network intervention versus individual hypertension counseling to improve blood pressure control after stroke. The investigators hope to understand whether the involvement of family, friends and other members of individual's social network can help achieve better blood pressure after experiencing a stroke. Participants will be stratified to two groups according to network size (\<5 vs 5 or more) and randomized to receive individual hypertension counseling (control) or the social network intervention. The primary outcome of the study will be the absolute reduction in systolic blood pressure at 3 months follow-up. The secondary outcomes will be attainment of a post-stroke hypertension treatment goal and patient-reported physical function.

Conditions

Stroke, Acute Ischemic; Hypertension

Keywords

Social Networks

Outcome Measures

Primary Outcomes (1)

• Change in Systolic Blood Pressure for Patient-Subjects

  Blood pressure was not collected for social network members.

  baseline and 3 months

Secondary Outcomes (2)

• Achievement of Post-stroke Hypertension Treatment Goal for Patient-Subjects

  3 months

• Patient Reported Physical Function for Patient-Subjets

  3 months

Study Arms (2)

Social Network Counseling

EXPERIMENTAL

The index patient and influential social network members will meet via Zoom 3 times over the course of 3 months with a clinical research nurse for teamwork counseling and blood pressure education.

Other: Social Network Group Counseling

Individual Counseling

ACTIVE COMPARATOR

The index patient will meet via Zoom 3 times over the course of 3 months with a clinical research nurse for blood pressure education.

Other: Individual Counseling

Interventions

Social Network Group Counseling OTHER

Researchers will identify the influential network members based on their network position, driving distance from the patient, speaking frequency, and whether they have high blood pressure. The index patient and social network members will meet with the study nurse on weeks 2, 6, and 12 after initial enrollment. The study nurse will begin the social network counseling session in which she will provide counseling on teamwork and blood pressure control. The teamwork specific topics will include how networks can work together as a team, communication tips for engaging with one another, spreading positive messages, and establishing the roles and responsibilities of each network team member. The blood pressure control specific topics will include the basics of blood pressure, taking and adjusting medications, monitoring blood pressure, reducing salt, and being physically active. Patient and social network members will receive text messages every week in the weeks between sessions.

Social Network Counseling

Individual Counseling OTHER

The index patient will meet individually with the study nurse on weeks 2, 6, and 12 after initial enrollment. The nurse will provide counseling on the basics of blood pressure, taking and adjusting medications, monitoring blood pressure, reducing salt, and being physically active. The patient will receive text messages every week in the weeks between sessions.

Individual Counseling

Eligibility Criteria

• Age: 21 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• First acute ischemic stroke defined clinically with support from imaging if necessary
• years of age or older
• Within 14 days after stroke
• History of hypertension or has been newly prescribed blood pressure medications during index admission

You may not qualify if:

• Prior ischemic or hemorrhagic stroke
• NIHSS \> 21
• Significant aphasia (Score\>1 on the language section of the NIHSS)
• Medical conditions for which death is likely within 6 months
• Does not have capacity to consent for the project or participate in survey interview
• Diagnosis of dementia
• Patient has no phone or incapable of using text messages
• Patient has opted out of participating in research noted within MGB Epic EHR system

Sponsors & Collaborators

• Brigham and Women's Hospital: lead
• National Institute on Aging (NIA): collaborator

Study Sites (1)

Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States

Location

Related Publications (1)

• Dhand A, Crum K, Hanken KE, Bhatkhande G, Luo M, Corbin IM, Usmanov G, Rothfeld-Wehrwein Z, Dhongade V, Lin D, Slocum C, Haff N, Choudhry NK. Social network intervention to improve blood pressure control after stroke: The TEAMS-BP randomized clinical trial. Soc Sci Med. 2025 Sep;380:118231. doi: 10.1016/j.socscimed.2025.118231. Epub 2025 May 21.

  PMID: 40414088 DERIVED

MeSH Terms

Conditions

Ischemic Stroke; Hypertension

Condition Hierarchy (Ancestors)

Stroke; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Results Point of Contact

• Title: Amar Dhand, MD, PhD
• Organization: Brigham and Women's Hospital

adhand@bwh.harvard.edu

617-732-7432

Study Officials

• Amar Dhand, MD, PhD

  Brigham and Women's Hospital

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor of Neurology

Study Record Dates

• First Submitted: February 17, 2022
• First Posted: February 28, 2022
• Study Start: May 31, 2022
• Primary Completion: January 26, 2024
• Study Completion: January 27, 2024
• Last Updated: March 26, 2025
• Results First Posted: March 26, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)