Motivational Interviewing to Address Suicidal Ideation for Veterans at High Risk for Suicide

NCT05256940 | Active Not Recruiting DMC

• 2 other identifiers: MHBC-001-21SI01CX002359
• Study Type: interventional
• Target: 368
• Locations: 1 country
• Sites: 3

Brief Summary

The purpose of this project is to conduct a randomized control trial with 470 Veterans to examine the impact of a revised version of Motivational Interviewing to Address Suicidal Ideation (MI-SI-R) on risk for suicide attempts and suicidal ideation when compared to high quality usual care.

Conditions

Suicide, Attempted; Suicidal Ideation

Keywords

veterans; motivational interviewing

Outcome Measures

Primary Outcomes (2)

• Columbia-Suicide Severity Rating Scale

  The first primary outcome is the presence (vs. absence) of non-fatal suicide attempts as reported on the Columbia-Suicide Severity Rating Scale.

  12-months

• Beck Scale for Suicidal Ideation

  The second primary outcome is suicidal ideation as reported on the Beck Scale for Suicidal Ideation, which has a range from 0-38, with higher scores indicating more severe suicidal ideation.

  12-month

Study Arms (2)

Motivational Interviewing to Address Suicidal Ideation- Revised (MI-SI-R)

EXPERIMENTAL

Motivational Interviewing to Address Suicidal Ideation (MI-SI-R) was developed to help Veterans resolve ambivalence about living by increasing the motivation to live, and is delivered in three sessions in person, virtually, or by telephone.

Behavioral: Motivational Interviewing to Address Suicidal Ideation- Revised (MI-SI-R); Other: Enhanced usual care (EUC)

Enhanced usual care (EUC)

ACTIVE COMPARATOR

Enhanced usual care (EUC) includes safety plans administered or reviewed by research therapists, care coordination, and access to a 24-hour crisis hotline.

Other: Enhanced usual care (EUC)

Interventions

Enhanced usual care (EUC) OTHER

Enhanced usual care (EUC) includes safety plans administered or reviewed by research therapists, care coordination, and access to a 24-hour crisis hotline.

Enhanced usual care (EUC); Motivational Interviewing to Address Suicidal Ideation- Revised (MI-SI-R)

Motivational Interviewing to Address Suicidal Ideation- Revised (MI-SI-R) BEHAVIORAL

Motivational Interviewing to Address Suicidal Ideation (MI-SI-R) was developed to help Veterans resolve ambivalence about living by increasing the motivation to live, that is delivered in three sessions in person, virtually, or by telephone.

Motivational Interviewing to Address Suicidal Ideation- Revised (MI-SI-R)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Veteran status,
• admitted to an inpatient unit, referred by a suicide prevention coordinator, or identified as high-risk via data extraction,
• age 18 and over,
• English speaking and reading, and
• ability to understand the study and provide informed consent,
• high-risk status confirmed by suicide attempt within a month on the Columbia- Suicide Severity Rating Scale or a score \> 5 on the Scale for Suicidal Ideation

You may not qualify if:

• current psychosis,
• active mania,
• dementia,
• impaired decision making capacity, and
• institutionalization due to hospitalization in a non-VA facility, jail, or prison.

Sponsors & Collaborators

• Portland VA Medical Center: collaborator
• Ralph H. Johnson VA Medical Center: collaborator
• VA Office of Research and Development: lead
• Syracuse VA Medical Center: collaborator

Study Sites (3)

VA Finger Lakes Healthcare System, Canandaigua, NY

Canandaigua, New York, 14424-1159, United States

Location

VA Portland Health Care System, Portland, OR

Portland, Oregon, 97207-2964, United States

Location

Ralph H. Johnson VA Medical Center, Charleston, SC

Charleston, South Carolina, 29401-5703, United States

Location

MeSH Terms

Conditions

Suicide, Attempted; Suicidal Ideation

Condition Hierarchy (Ancestors)

Suicide; Self-Injurious Behavior; Behavioral Symptoms; Behavior

Study Officials

• Peter C. Britton, PhD MS

  VA Finger Lakes Healthcare System, Canandaigua, NY

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: Outcome assessors will be blinded to treatment received by participants.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: FED
• Responsible Party: SPONSOR

Model Details: Motivational Interviewing to Address Suicidal Ideation (MI-SI-R) was developed to help participants at high-risk for suicide resolve their ambivalence about living by increasing their motivation to live, and is delivered in three sessions in-person, virtually, or by telephone.

Study Record Dates

• First Submitted: February 16, 2022
• First Posted: February 25, 2022
• Study Start: November 30, 2022
• Primary Completion: March 31, 2026
• Study Completion (Estimated): June 29, 2027
• Last Updated: April 24, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will share
• Shared Documents: CSR
• Time Frame: Limited data sets will be available per a Data Use Agreement (DUA), which will determine the time frame.
• Access Criteria: Limited data will be provided after requestors sign a Data Use Agreement (DUA).

Locations

US (3)