Comparison Between Different Psychotherapy Interventions Regarding Their Effect on Substance Craving

NCT05256485 | Completed

• 1 other identifier: RPC£0521190906
• Study Type: interventional
• Target: 45
• Locations: 1 country
• Sites: 1

Brief Summary

the study aim is to compare betwenn the effect of mindfulness based relapse prevention and other evidence based psychotherapy interventions regaring substance craving.

Conditions

Addiction Opiate

Outcome Measures

Primary Outcomes (1)

• opioid craving scale

  A visual analog scale, a modification of the Cocaine Craving Scale, is a 3-item scale used to measure the opioid craving and each item is ranging from 0 to 10 (0 means no craving at all and 10 means severe craving).

  5 minutes

Secondary Outcomes (2)

• The Obsessive-Compulsive Drug use Scale

  15 minutes

• The desire for a drug questionnaire

  15 minutes

Study Arms (3)

cognitive behavioral therapy

ACTIVE COMPARATOR

Standard CBT comprises an array of approaches directed toward modifying dysfunctional thinking and behavior. The two critical components are analysis of thoughts, feelings, and behaviors, as well as skills training for achieving active behavior and thought modification.

Behavioral: cognitive behavioral therapy,mindfulness based relapse prevention,twelve-step therapy

mindfulness based relapse prevention

ACTIVE COMPARATOR

MBRP training is based on a two-component process: 1. Attention to present moment experience, even if it includes craving or negative emotion. 2. An accepting attitude towards this experience letting it be exactly as it is, without judging it or reacting to it.

Behavioral: cognitive behavioral therapy,mindfulness based relapse prevention,twelve-step therapy

twelve-step therapy

ACTIVE COMPARATOR

12-step therapy was based on strengthening conscious contact with God and awakening spirituality through prayer and meditation

Behavioral: cognitive behavioral therapy,mindfulness based relapse prevention,twelve-step therapy

Interventions

cognitive behavioral therapy,mindfulness based relapse prevention,twelve-step therapy BEHAVIORAL

In cognitive-behavioral therapy, participants learned that thoughts and emotions contribute to behavior, and responses to thoughts and emotions can be controlled. in mindfulness-based relapse prevention, participants learned to focus on the present moment experience including craving with an attitude of acceptance and non-judging. In twelve-step therapy, participants learned principles of acceptance, gratitude, forgiveness, tolerance, patience, humility, and honesty together with participation in different healthy ways to enrich life.

cognitive behavioral therapy; mindfulness based relapse prevention; twelve-step therapy

Eligibility Criteria

• Age: 15 Years - 50 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Age: 15-50 years.
• Male gender.
• Patients meet DSM-5(3) criteria of opioid abuse.
• Had completed detoxification in a treatment center.
• Willing to give consent they will be randomly assigned to either CBT, MBRP, or twelve-step treatment group.
• Patients have dual diagnoses.
• Patients have poly-substance use disorder.

You may not qualify if:

• Participants with significant cognitive disorder.
• Participants with suicidal thoughts.
• Participants with any organic condition affecting stress response and so craving such as hypertension, respiratory or cardiovascular disorders.
• Participants taking any medications (e.g., antipsychotics in high doses) known to affect the stress response.
• Participants relapsed to drug abuse during therapy.

Sponsors & Collaborators

• Sara Harby: lead

Study Sites (1)

Sara Harby

Alexandria, 03, Egypt

Location

MeSH Terms

Conditions

Opioid-Related Disorders

Interventions

Cognitive Behavioral Therapy

Condition Hierarchy (Ancestors)

Narcotic-Related Disorders; Substance-Related Disorders; Chemically-Induced Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Behavior Therapy; Psychotherapy; Behavioral Disciplines and Activities

Study Officials

• Tarek K Molokhia, Phd

  professor of neuropsychiatry

  STUDY CHAIR

• Osama A Elkholy, Phd

  professor of neuropsychiatry

  STUDY CHAIR

• Ahmed M Abdelkreem, Phd

  lecturer of neuropsychiatry

  STUDY DIRECTOR

• Sara A Harby, master

  assistant lecturer of psychiatry

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: assistant lecturer

Model Details: Standard cognitive behavioral therapy comprises approaches directed toward modifying dysfunctional thinking and behavior discussed through 8 sessions. mindfulness based relapse prevention is an 8-week therapy program based on: 1. Attention to present moment experience, even if it includes craving or negative emotion. 2. An accepting attitude towards this experience letting it be exactly as it is, without judging it or reacting to it. This group therapy was facilitated by an ex-addict working in El Maamora hospital. 12-step therapy was based on strengthening conscious contact with God and awakening spirituality through prayer and meditation.

Study Record Dates

• First Submitted: February 8, 2022
• First Posted: February 25, 2022
• Study Start: October 15, 2019
• Primary Completion: June 30, 2021
• Study Completion: October 10, 2021
• Last Updated: February 25, 2022

Record last verified: 2022-02

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)