Risk of Acute Kidney Injury in Living Liver Donor Surgery

NCT05255510 | Completed

• 1 other identifier: AnkaraUni
• Study Type: observational
• Target: 130
• Locations: 1 country
• Sites: 1

Brief Summary

Acute kidney injury (AKI) is one of the most common complication after restricted fluid therapy for major surgery. The aim of this study is to evaluate the incidence of AKI as defined by Kidney Disease Improving Global Outcomes (KDIGO) criteria in living liver donor hepatectomy in which applied intraoperative protocolized fluid restriction targeting a low central venous pressure (CVP) level and high pulse pressure variation (PPV) / systolic pressure variation (SPV).

Conditions

Acute Kidney Injury; Liver Transplant; Complications; Fluid and Electrolyte Imbalance

Keywords

Living donors; acute kidney injury; central venous pressure; Hemodynamic Monitoring; fluid therapy

Outcome Measures

Primary Outcomes (1)

• Acute kidney injury in living donor patients

  Kidney Disease Improving Global Outcomes (KDIGO) criteria

  one week

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

patients who underwent living liver donor hepatectomy

You may qualify if:

• patients who underwent living liver donor hepatectomy

Sponsors & Collaborators

• Ankara University: lead
• Elvan Onur Kırımker: collaborator
• Sevcan Büyük: collaborator
• Elif Beyza Baskan: collaborator
• Ali Abbas Yılmaz: collaborator
• Deniz Balcı: collaborator
• Kaan Karayalçın: collaborator
• Mustafa Kemal Bayar: collaborator

Study Sites (1)

Süheyla Karadağ Erkoç

Ankara, 06230, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Acute Kidney Injury

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases

Study Officials

• Süheyla Karadağ Erkoç

  Ankara University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Anesthesiology and Reanimation

Study Record Dates

• First Submitted: February 14, 2022
• First Posted: February 24, 2022
• Study Start: October 10, 2019
• Primary Completion: June 1, 2020
• Study Completion: June 10, 2021
• Last Updated: May 12, 2022

Record last verified: 2022-05

Locations

TU (1)