The Effect of Different Methods for Modulating Postprandial Fat Oxidation on Postprandial Lipemia the Next Day
Time-restricted Feeding Increases Fat Oxidation Rate But Not Affect Postprandial Lipemia: a Crossover Trial
1 other identifier
interventional
8
1 country
1
Brief Summary
Background: Studies have revealed that time-restricted feeding affects the fat oxidation rate; however, its effects on the fat oxidation rate and hyperlipidemia following high-fat meals are unclear. This study investigated the effects of 5-day time-restricted feeding on the fat oxidation rate and postprandial lipemia following high fat meals. Methods: In this random crossover experimental study, eight healthy male adults were included each in the 5-day time-restricted feeding trial and the control trial. The meals of the time-restricted feeding trial were provided at 12:00, 16:00, and 20:00. The meals of the control trial were provided at 08:00, 14:00, and 20:00. The contents of the meals of both trials were the same, and the calories of the meals met the 24-hour energy requirement of the participants. After 5 days of the intervention, the participants consumed high-fat meals on the sixth day, and their physiological changes were determined.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Jun 2021
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 4, 2021
CompletedFirst Submitted
Initial submission to the registry
February 2, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 3, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
February 3, 2022
CompletedFirst Posted
Study publicly available on registry
February 22, 2022
CompletedFebruary 22, 2022
February 1, 2022
8 months
February 2, 2022
February 17, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (5)
postprandial triglycerides concentrations
postprandial triglycerides concentrations (mmol/L)
on the 6th day
postprandial glucose concentrations
postprandial glucose concentrations (mmol/L)
on the 6th day
postprandial insulin concentrations
postprandial insulin concentrations (pmol/L)
on the 6th day
postprandial free fatty acid concentrations
postprandial FFA concentrations (mmol/L)
on the 6th day
postprandial glycerol concentrations
postprandial glycerol concentrations (umol/L)
on the 6th day
Secondary Outcomes (1)
fat oxidation
on the 6th day
Study Arms (2)
time-restricted feeding trial
EXPERIMENTALThe participants were divided into the time-restricted feeding trial for 5 days
control trial
EXPERIMENTALThe participants in the control trial did not practice intermittent fasting methods
Interventions
The 5-day time-restricted feeding trial and the control trial. The meals of the time-restricted feeding trial were provided at 12:00, 16:00, and 20:00.
Eligibility Criteria
You may qualify if:
- All the participants had not undergone physical training;
- they did not exercise regularly;
- and they did not have any diseases that would prevent them from performing exercises, such as high blood pressure, hyperlipidemia, heart disease, joint disease, and osteoporosis.
You may not qualify if:
- Undergone physical training;
- Exercise regularly;
- Have any diseases that would prevent them from performing exercises, such as high blood pressure, hyperlipidemia, heart disease, joint disease, and osteoporosis.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
National Taiwan University of Sport
Taichung, 404, Taiwan
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
ChihHui Chiu, PhD
National Taiwan University of Sport
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
February 2, 2022
First Posted
February 22, 2022
Study Start
June 4, 2021
Primary Completion
February 3, 2022
Study Completion
February 3, 2022
Last Updated
February 22, 2022
Record last verified: 2022-02