NCT05247892

Brief Summary

The investigators aim to compare the effect of ultrasound versus floroscopy guided pulsed radiofrequency treatment of the lumbar dorsal root ganglion (DRG) of S1 in patients with a chronic lumbosacral radicular pain.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 1, 2022

Completed
Same day until next milestone

Study Start

First participant enrolled

February 1, 2022

Completed
20 days until next milestone

First Posted

Study publicly available on registry

February 21, 2022

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 10, 2022

Completed
10 days until next milestone

Study Completion

Last participant's last visit for all outcomes

October 20, 2022

Completed
Last Updated

November 2, 2022

Status Verified

October 1, 2022

Enrollment Period

8 months

First QC Date

February 1, 2022

Last Update Submit

October 31, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Pain scores

    Visual analog scale (VAS) for pain at the follow-up time periods. The visual analog scale is a numerical scale from 0 to 10; with 0 representing no pain and 10 representing the worst pain imaginable.

    baseline to 6 months post-procedure

Secondary Outcomes (2)

  • Oswestry Disability Index (ODI)

    baseline to 6 months post-procedure

  • Patient satisfaction Questionnaire

    baseline to 6 months post-procedure

Study Arms (2)

Fluoroscopic-guided S1 Radiofrequency stimulation

ACTIVE COMPARATOR
Procedure: Fluoroscopic-guided S1 Radiofrequency stimulation

Ultrasound-guided S1 Radiofrequency stimulation

EXPERIMENTAL
Procedure: Ultrasound-guided S1 Radiofrequency stimulation

Interventions

Pulsed radiofrequency stimulation of the S1 dorsal root ganglia under ultrasound-guidance

Ultrasound-guided S1 Radiofrequency stimulation

Pulsed radiofrequency stimulation of the S1 dorsal root ganglia under fluoroscopy-guidance

Fluoroscopic-guided S1 Radiofrequency stimulation

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Persistent pain score ≥ 4 on VAS, not responding to traditional treatments
  • Radicular pain in lumbar region for 3 months or more,
  • Pattern of radiation suggestive for S1 pathology

You may not qualify if:

  • Patient refusal
  • Coagulopathy
  • Uncooperative patients
  • Malignant disorder or currently under treatment for a malignant disorder
  • Pregnancy
  • Leg pain due to localized hip or knee pathology

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Diskapi Yildirim Beyazit Training and Research Hospital

Ankara, 06110, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Chronic Pain

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Medical Doctor

Study Record Dates

First Submitted

February 1, 2022

First Posted

February 21, 2022

Study Start

February 1, 2022

Primary Completion

October 10, 2022

Study Completion

October 20, 2022

Last Updated

November 2, 2022

Record last verified: 2022-10

Locations