NCT05242536

Brief Summary

The aim of this study is to examine the effectiveness of nurse- led program on psychosocial problems and quality of life in stroke patients. This randomized controlled trial will be conducted in Stroke Center in Istinye University Liv Hospital-Bahcesehir. Eligible participants will be randomly allocated to either the control group (receiving usual care/ routine follow-up group) or the intervention group (receiving nurse-led psychosocial program). A nurse- led program will be implemented for the management of psychosocial problems following a comprehensive evaluation. Then, the effect of this program on psychosocial problems and quality of life will be evaluated in the 1st and 3rd months after discharge.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
70

participants targeted

Target at P50-P75 for not_applicable stroke

Timeline
Completed

Started Nov 2021

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2021

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

January 23, 2022

Completed
24 days until next milestone

First Posted

Study publicly available on registry

February 16, 2022

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2022

Completed
Last Updated

February 16, 2022

Status Verified

February 1, 2022

Enrollment Period

1 year

First QC Date

January 23, 2022

Last Update Submit

February 5, 2022

Conditions

Keywords

StrokePsychosocial ProblemNurse-led ProgramQuality of Life

Outcome Measures

Primary Outcomes (3)

  • Change in Montreal Cognitive Assessment Test scores

    Cognitive function will be evaluated by Montreal Cognitive Assessment Test.

    At the baseline, 1st and 3rd month after discharge

  • Change in Hospital Anxiety and Depression Scale scores

    Anxiety and depression will be evaluated by Hospital Anxiety and Depression Scale.

    At the baseline, 1st and 3rd month after discharge

  • Change in Pittsburgh Sleep Quality Index scores

    Sleep quality will be evaluated by Pittsburgh Sleep Quality Index.

    At the baseline, 1st and 3rd month after discharge

Secondary Outcomes (3)

  • Change in Fatigue Severity Scale scores

    At the 1st and 3rd month after discharge

  • Change in Reintegration to Normal Living Index scores

    At the 1st and 3rd month after discharge

  • Change in Stroke Specific Quality of Life Scale scores

    At the 1st and 3rd month after discharge

Study Arms (2)

Nurse- led program

EXPERIMENTAL

A nurse coordinated multidisciplinary program aiming to improve psychosocial problems has been developed and will be applied to the patients in the experimental group. This nurse-led program will start at discharge and continue for three months.

Other: Nurse- led program

Routine follow-up group

NO INTERVENTION

The control group will be applied usual care. Patients in the control group will be discharged by receiving standard care and performing discharge trainings used in the routine care.

Interventions

A nurse coordinated multidisciplinary program aiming to improve psychosocial problems has been developed and will be applied to the patients in the experimental group. This nurse-led program will start at discharge and continue for three months.

Nurse- led program

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Be literate
  • Have a clinical diagnosis of ischemic stroke
  • History of any preceding cerebral vascular event
  • Capable of giving informed consent

You may not qualify if:

  • Age ≤ 18 years
  • Have a mental disorder that will prevent cognitive evaluation
  • Have an impaired consciousness (confusion, delirium, etc.)
  • History of any type of cognitive decline
  • Have severe neurologicial deficit
  • Severe aphasia
  • Living in a nursing home
  • Known malignant disease or other chronic disease with poor prognosis and a low life expectancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Stroke Center in Istinye University Liv Hospital-Bahcesehir

Istanbul, 34510, Turkey (Türkiye)

RECRUITING

Related Publications (2)

  • Verberne DPJ, Kroese MEAL, Staals J, Ponds RWHM, van Heugten CM. Nurse-led stroke aftercare addressing long-term psychosocial outcome: a comparison to care-as-usual. Disabil Rehabil. 2022 Jun;44(12):2849-2857. doi: 10.1080/09638288.2020.1849417. Epub 2020 Nov 26.

    PMID: 33242261BACKGROUND
  • Lanctot KL, Lindsay MP, Smith EE, Sahlas DJ, Foley N, Gubitz G, Austin M, Ball K, Bhogal S, Blake T, Herrmann N, Hogan D, Khan A, Longman S, King A, Leonard C, Shoniker T, Taylor T, Teed M, de Jong A, Mountain A, Casaubon LK, Dowlatshahi D, Swartz RH; Management of Mood, Cognition and Fatigue Following Stroke Best Practice Writing Group, the Heart & Stroke Canadian Stroke Best Practices and Quality Advisory Committee; in collaboration with the Canadian Stroke Consortium. Canadian Stroke Best Practice Recommendations: Mood, Cognition and Fatigue following Stroke, 6th edition update 2019. Int J Stroke. 2020 Aug;15(6):668-688. doi: 10.1177/1747493019847334. Epub 2019 Jun 21.

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Hilalnur Kucukakgun, RN,MSc

    Istanbul University - Cerrahpasa

    PRINCIPAL INVESTIGATOR
  • Zeliha Tulek, RN,Assoc Prof

    Istanbul University - Cerrahpasa

    STUDY DIRECTOR
  • Yakup Krespi, MD, Prof

    Istinye University Liv Hospital- Bahcesehir

    STUDY CHAIR

Central Study Contacts

Hilalnur Kucukakgun, RN, MSc

CONTACT

Zeliha Tulek, RN, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assoc.Prof

Study Record Dates

First Submitted

January 23, 2022

First Posted

February 16, 2022

Study Start

November 1, 2021

Primary Completion

November 1, 2022

Study Completion

November 1, 2022

Last Updated

February 16, 2022

Record last verified: 2022-02

Data Sharing

IPD Sharing
Will not share

Locations