Gastric Residual Volume Measurement in the Intensive Care Unit

NCT05238051 | Completed

• 1 other identifier: GRVROLE
• Study Type: interventional
• Target: 74
• Locations: 1 country
• Sites: 1

Brief Summary

Nutritional support is considered a key component of the treatment strategy for intensive care patients. Malnutrition, energy protein, and inadequate or excessive intake of other nutrients have measurable effects on tissues, body structure, body function, and clinical outcomes of patients receiving treatment. It increases hospital-acquired infections, hospitalizations, and intensive care prolongs and leads to complications. This study aimed to observe the time to reach target calories, nutritional failures, and complications during feeding in measured and unmeasured gastric residual volume patients receiving enteral nutrition under ventilation in the intensive care unite.

Conditions

Preventing Malnutrition

Keywords

gastric residual volume; malnutrition; target calorie; intensive care unit; enteral nutrition

Outcome Measures

Primary Outcomes (1)

• The difference in the time to reach target calories in patients with gastric residual volume measurement compared to those without gastric residual volume measurement.

  The difference in the time to reach target calories in patients with gastric residual volume measurement compared to those without gastric residual volume measurement.

  10 days

Study Arms (2)

Gastric residual volume group

NO INTERVENTION

Patients undergoing enteral nutrition with continuous infusion and intermittent gastric residual volume measurement in the intensive care unit

Non- Gastric residual volume group

EXPERIMENTAL

Patients undergoing enteral nutrition with continuous infusion and intermittent gastric residual volume measurement was not measured in the intensive care unit

Other: Gastric residual volume measurement stopped.

Interventions

Gastric residual volume measurement stopped. OTHER

GRV is checked during routine enteral nutrition, but we think that GRV prolongs the time to reach target calories and does not reduce complications.

Non- Gastric residual volume group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Mechanical ventilatory support
• open enteral route (nasogastric/PEG)

You may not qualify if:

• History of gastrointestinal bleeding,
• parenteral nutrition support,
• hospital stay of fewer than two days,
• under 18 years of age

Sponsors & Collaborators

• Erzincan Binali Yildirim Universitesi: lead

Study Sites (1)

Erzincan Binali Yildirim university

Erzincan, 24100, Turkey (Türkiye)

Location

Related Publications (2)

• Marik PE. Enteral nutrition in the critically ill: myths and misconceptions. Crit Care Med. 2014 Apr;42(4):962-9. doi: 10.1097/CCM.0000000000000051.

  PMID: 24296860 BACKGROUND

• Elke G, Felbinger TW, Heyland DK. Gastric residual volume in critically ill patients: a dead marker or still alive? Nutr Clin Pract. 2015 Feb;30(1):59-71. doi: 10.1177/0884533614562841. Epub 2014 Dec 18.

  PMID: 25524884 BACKGROUND

MeSH Terms

Conditions

Malnutrition

Condition Hierarchy (Ancestors)

Nutrition Disorders; Nutritional and Metabolic Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: Gastric residual volume (GRV) was measured in one group and not in the other. Nutrition was started at an infusion rate of 20 ml/hour in the GRV group. The GRV was measured every four hours. When it was less than 200 ml, the infusion rate was increased by 20 ml/hour. The infusion rate, which was increased every four hours according to the GRV, was continued constantly when the target calorie was reached. It was kept constant when the GRV was above 200 ml, and then the feeding rate was reduced to half when the GRV volume was above 400 ml. In four patients, enteral nutrition was discontinued due to melena and excluded from the study. In six patients with persistently high GRV values, enteral nutrition was discontinued and parenteral nutrition initiated. The study was completed with 62 patients. GRV (n=31) and Non-GRV (n=31).

Study Record Dates

• First Submitted: January 21, 2022
• First Posted: February 14, 2022
• Study Start: March 1, 2021
• Primary Completion: January 1, 2022
• Study Completion: January 20, 2022
• Last Updated: February 14, 2022

Record last verified: 2022-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)