Chemotherapy Oral Manifestations and Dental Awareness Among Parents

NCT05224882 | Unknown

• 1 other identifier: Chemotherapy manifestations
• Study Type: observational
• Target: 441
• Locations: 0 countries
• Sites: N/A

Brief Summary

The prevention of oral illnesses in children and adolescents undergoing oncological treatment is critical, because oral lesions caused by this therapy significantly exacerbate the clinical condition and increase the risk of infection, as well as making it harder to perform required dental procedures when needed . "The key to success in maintaining a healthy oral cavity during therapy is patient compliance. The child and the parents should be educated regarding the possible acute side effects." Pediatric cancer patients may have a lower quality of life if they have poor dental health. Preventing and treating pre-existing oral illnesses is critical to reduce problems in these people. It is critical to raise awareness of the benefits of proper oral health so that this understanding becomes a positive attitude, reducing the discomfort of these children. The American Academy of Pediatric Dentistry (AAPD) recommends pediatric oncology/hematology that Pediatric dentists must be involved in the treatment process from the moment cancer is diagnosed. This should be carried out by having a preventive and dental care plan developed based on the patient's needs before any cancer treatment is initiated. The aim of the study is primarily to report oral complications and manifestations during chemotherapy treatment in pediatric cancer patients and raise the awareness of their parents on these manifestations thus proper interventions can be carried out to prevent more serious problems.

Conditions

Mucositis Oral; Chemotherapy Effect

Outcome Measures

Primary Outcomes (1)

• The assessment of the prevalence of oral adverse events induced by chemotherapy in pediatric cancer patients .

  Patients will be examined for oral manifestations at the first visit together with intra oral photos will be taken for the patients included in the study. Voice ,swallow ,tongue, saliva, mucous membrane\*\*, gingiva ,teeth will be measured by Oral Assessment Guide by the principal investigator . \*\*If oral mucositis is present it will be staged according to the World Health Organization Scale (WHO Oral Toxicity Scale) by the principal investigator.

  Baseline

Secondary Outcomes (1)

• Assessment of dental awareness among parents of pediatric cancer patients .

  Baseline

Eligibility Criteria

• Age: 1 Year - 14 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Probability Sample

Study Population

The study will be carried out at the pediatric clinic of the National Cancer Institute ,Egypt. Pediatric patients and their parents at the pediatric clinic will be screened until the target population is achieved. The pediatric patients will be subjected to thorough examination. Once the patient and the parent are potentially eligible for this study, the principal investigator will explain the study and ascertain the patient's and the parents' interest. The legal guardian provides written informed consent for participation in the study.

You may qualify if:

• Children between the age of 1 -14years.
• Children receiving chemotherapy for hematological cancer or solid tumors.
• Parents who are able to understand the aim of the study and willing to participate in the study.

You may not qualify if:

• Children previously received radiotherapy on head and neck region.
• Children suffering from oral cancer.
• Children presented with other oral disorders such as leukoplakia.

Sponsors & Collaborators

• Cairo University: lead

MeSH Terms

Conditions

Stomatitis

Condition Hierarchy (Ancestors)

Mouth Diseases; Stomatognathic Diseases

Study Officials

• Sherif Bahgat, Professor

  Professor of Pediatric Dentistry and Dental Public Health, Faculty of Dentistry, Cairo University.

  STUDY CHAIR

Central Study Contacts

Amira M Al-Naggar, B.D.S

CONTACT

01125355552; Amira_mohammed@dentistry.cu.edu.eg

Yasmin Yousry, PHD

CONTACT

01008486467

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: January 25, 2022
• First Posted: February 4, 2022
• Study Start: August 12, 2023
• Primary Completion: November 27, 2023
• Study Completion: January 25, 2024
• Last Updated: November 29, 2022

Record last verified: 2022-11