Contribution of SuPAR for Patients in a Situation of Uncertainty Downstream of Emergencies

NCT05214534 | Completed

• 2 other identifiers: RNI 2021 MOUSTAFA2021-A01930-41
• Study Type: observational
• Target: 202
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, the investigators will investigate the relationship between the blood level of SuPAR at admission to the emergency department of the Clermont-Ferrand University Hospital, and the outcome of patients after their hospitalization in a short stay unit.

Conditions

Emergencies; Disease; In-hospital Observation

Keywords

Supar; Patient triage; Emergency

Outcome Measures

Primary Outcomes (1)

• Relationship between blood supar levels and patient outcome at discharge

  Relation between blood supar levels measured and patient outcome at discharge evaluated as : return home = good evolution; hospitalization = bad evolution; admission to an intensive care unit or death = unfavorable evolution

  When the excepted 150 patients will be included, estimated 6 months

Secondary Outcomes (11)

• National Early Warning Score 2 (NEWS2)

  Hour 0

• Modified Early Warning Score (MEWS)

  Hour 0

• Blood supar levels

  When the excepted 150 patients will be included, estimated 6 months

• Blood CRP value

  Hour 0

• Cardiac frequency

  Hour 0

Study Arms (1)

Experimental

Retrospective analysis of the correlation between SuPAR measurement and patient outcome after hospitalization

Other: blood supar measurement

Interventions

blood supar measurement OTHER

The supar values will be measured afterwards on the tube bottoms of the patients included in the study from their usual collection

Experimental

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

all patients requiring clinical observation for a final referral decision and meeting the eligibility criteria will be offered the study

You may qualify if:

• Patient, male or female, over 18 years old
• Admitted to the emergency department of the Clermont-Ferrand University Hospital for a medical reason,
• Classified as FRENCH II or III by the nurse organizer of the reception management
• Necessity of clinical observation in the Short Term Hospitalization Unit for final orientation decision
• Requires a blood test upon arrival in the emergency department
• Able to give informed non-opposition to participate in the research.
• Affiliation to a Social Security system

You may not qualify if:

• Patient under guardianship or curatorship
• Pregnant and breast feeding woman
• Patient admitted for psychiatric pathology
• Patient with a limitation of therapeutics
• Refusal to participate
• Patient hospitalized because of a particular social context

Sponsors & Collaborators

• University Hospital, Clermont-Ferrand: lead

Study Sites (1)

CHU clermont-ferrand

Clermont-Ferrand, France

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

bottoms of the of blood sample

MeSH Terms

Conditions

Emergencies; Disease

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Farès Moustafa

  University Hospital, Clermont-Ferrand

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 8, 2021
• First Posted: January 28, 2022
• Study Start: January 10, 2022
• Primary Completion: April 18, 2022
• Study Completion: April 18, 2022
• Last Updated: March 13, 2023

Record last verified: 2021-11

Locations

FR (1)