RBG: Regular, Bare, Gel: Does Type of Nail Polish Affect Bacterial Counts After Surgical Scrubbing?

NCT05210920 | Completed

• 1 other identifier: 21-0027
• Study Type: interventional
• Target: 53
• Locations: 1 country
• Sites: 1

Brief Summary

Purpose: The purpose of this study is to evaluate if type of nail polish (gel polish or regular polish) has an effect on the number of bacterial colonies on finger nails after surgical scrubbing. Participants: The potential participants are healthcare providers with patient interaction. Exclusion criteria include evidence of active dermatitis or other skin abnormalities, or allergy to chlorhexidine. Intervention: Participants will have gel nail polish applied to one finger of their dominant hand, and regular polish applied to another finger of their dominant hand. Bacterial swabs will be collected from these two fingers, as well as the from the adjacent finger with no nail polish. Specimen collection will occur both before and after scrubbing with surgical soap. Bacterial counts will be compared between the three groups to determine the association between the presence of nail polish and nail polish type on bacterial counts after surgical scrubbing. Specimen collection will not take place during scrubbing for actual patient care.

Conditions

Bacterial Infections; Surgical Site Infection; Contaminated Medical or Biological Substances

Outcome Measures

Primary Outcomes (4)

• Bacterial Counts Before Scrubbing Day 1-3

  Bacterial colony counts will be measured from each swab obtained from the three types of fingernails (regular polish, gel polish, bare nail).

  1-3 days after polish application

• Bacterial Counts After Scrubbing Day 1-3

  Bacterial colony counts will be measured from each swab obtained from the three types of fingernails (regular polish, gel polish, bare nail).

  1-3 days after polish application

• Bacterial Counts Before Scrubbing Day 5-7

  Bacterial colony counts will be measured from each swab obtained from the three types of fingernails (regular polish, gel polish, bare nail).

  5-7 days after polish application

• Bacterial Counts After Scrubbing Day 5-7

  Bacterial colony counts will be measured from each swab obtained from the three types of fingernails (regular polish, gel polish, bare nail).

  5-7 days after polish application

Secondary Outcomes (4)

• Percent of nail polish flaking (%) Day 1-3

  1-3 days after polish application

• Percent of nail polish flaking (%) Day 5-7

  5-7 days after polish application

• Nail growth (mm) Day 1-3

  1-3 days after polish application

• Nail growth (mm) Day 5-7

  5-7 days after polish application

Study Arms (3)

Regular Nail Polish

EXPERIMENTAL

Participants will have regular nail polish applied to one fingernail of their dominant hand

Other: Nail polish application

Gel Nail Polish

EXPERIMENTAL

Participants will have gel nail polish applied to one fingernail of their dominant hand

Other: Nail polish application

Bare Nail

NO INTERVENTION

Participants will have one fingernail of their dominant hand left bare for comparison

Interventions

Nail polish application OTHER

After application of nail polish as described, participants will have bacterial swabs collected from the under the fingernail and from the nail bed of the three assigned fingers on their dominant hand, both before and after scrubbing with a chlorhexidine surgical scrubbing brush.

Gel Nail Polish; Regular Nail Polish

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Healthcare provider who provides patient care

You may not qualify if:

• Active dermatitis or other skin abnormality
• Allergy to chlorhexidine scrub soap

Sponsors & Collaborators

• University of North Carolina, Chapel Hill: lead

Study Sites (1)

UNC Chapel Hill

Chapel Hill, North Carolina, 27516, United States

Location

MeSH Terms

Conditions

Bacterial Infections; Surgical Wound Infection

Condition Hierarchy (Ancestors)

Bacterial Infections and Mycoses; Infections; Wound Infection; Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Elizabeth Geller, MD

  University of North Carolina, Chapel Hill

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: All participants will have all three nail types assessed: regular polish, gel polish and bare nail

Study Record Dates

• First Submitted: January 12, 2022
• First Posted: January 27, 2022
• Study Start: May 28, 2021
• Primary Completion: May 31, 2023
• Study Completion: May 31, 2023
• Last Updated: August 4, 2023

Record last verified: 2023-08

Data Sharing

• IPD Sharing: Will share
• Time Frame: The data will be available beginning 12 mos following publication and ending 24 months after publication.
• Access Criteria: Following approval from an appropriate review board as described above and execution of a data use/sharing agreement with UNC-Chapel Hill

Locations

US (1)