The Effect of Varying Brightness on Palpebral Aperture

NCT05210491 | Unknown

• 1 other identifier: 1062/RD
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

We aim to establish the point at which glare from bright lights begins to engage our eyelids - causing us to "squint". We will be using a video camera with an LED ring light around it facing the volunteer and we will record the eyelid position as the light brightness is increased gradually. Many studies have looked at the effect glare has on a person through qualitative questionnaires but few have been able to quantify this.

Conditions

Eyelid Ptoses

Keywords

Palpebral Aperture measurements

Outcome Measures

Primary Outcomes (1)

• The point at which the eyelid begins to contract under what brightness level

  Using a light meter, ring light, and EEG machine

  All carried out within a 2 week period

Study Arms (1)

The observation of eyelid positioning and EEG pulses from the eyelid on increasing brightness

EXPERIMENTAL

In a dimly lit room the participant will place their chin on the slit lamp We will use t he optimal background illumination used for Humphrey and Goldman visual fields which is 31.5 apostilbs (10Lux 9 They will look into the video camera placed 50cm away, which will have a dimmable remote control ring light fitted around it. The part icipant will have a reference measure taped to the headrest and three electrodes placed around the right eye. One active electrode place on the lower lid and one reference electrode towards the temporal margin and one earth electrode placed on the forehead The brightness of the ring light will be increased via the dimmer switch whilst simultaneously recording the lux with the LED light meter. The participant will be advised t o close their eyes if the brightness becomes uncomfortable and this will be repea ted three times.

Other: Review of eyelid positioning in increasing brightness levels

Interventions

Review of eyelid positioning in increasing brightness levels OTHER

Up to 30 seconds, three times, looking into a video camera as glare is incrementally increased.

The observation of eyelid positioning and EEG pulses from the eyelid on increasing brightness

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Aged between 18 and 65 years of age
• A member of the Royal Free NHS trust

You may not qualify if:

• No known ocular pathology
• No lid problems/ptosis or previous lid surgery
• No contact lenses in for duration of experiment
• No pseudophakia
• No neurological disease

Sponsors & Collaborators

• University of Edinburgh: lead
• National Health Service, United Kingdom: collaborator
• Royal Free Hospital NHS Foundation Trust: collaborator

Study Sites (1)

Ophthalmology, Royal Free Hospital

London, NW3 2QY, United Kingdom

Location

MeSH Terms

Conditions

Blepharoptosis

Condition Hierarchy (Ancestors)

Eyelid Diseases; Eye Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 14, 2022
• First Posted: January 27, 2022
• Study Start: January 14, 2022
• Primary Completion: February 21, 2022
• Study Completion: February 21, 2022
• Last Updated: January 27, 2022

Record last verified: 2022-01

Locations

GB (1)