Effect of Dragon Fruit Consumption in Individuals at Risk of Type 2 Diabetes
1 other identifier
interventional
20
1 country
1
Brief Summary
In this project, an edible product based on dragon fruit will be tested to determine its effect on blood glucose levels and blood pressure in individuals at risk of type 2 diabetes. The effect of a product from dragon fruit on fasting plasma glucose and blood pressure will be assessed by a parallel study design with two groups and 16 participants in each one. Secondary outcomes such as inflammation biomarkers, lipid profile and oxidative stress markers also will be determined in blood samples.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Jan 2022
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 6, 2022
CompletedFirst Posted
Study publicly available on registry
January 20, 2022
CompletedStudy Start
First participant enrolled
January 20, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 31, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2023
CompletedSeptember 6, 2023
September 1, 2023
1.6 years
January 6, 2022
September 4, 2023
Conditions
Outcome Measures
Primary Outcomes (2)
Blood glucose response
Blood glucose in venous blood sample
2 hours
Blood pressure
Systolic and diastolic blood pressure
15 minutes
Secondary Outcomes (3)
Plasma insulin response
2 hours
C-reactive protein
5 minutes
HbA1C
5 minutes
Study Arms (2)
Dragon fruit product
EXPERIMENTALA dragon fruit beverage
General health advice
NO INTERVENTIONBased on Eatwell guide and guidelines for type 2 diabetes prevention from the National Institute for Health and Care Excellence (NICE)
Interventions
Eligibility Criteria
You may qualify if:
- Have a first grade relative with diabetes (parent, brother, or sister)
- Have a BMI ≥ 25.0.
- Have a sedentary lifestyle.
You may not qualify if:
- Covid-19 related symptoms, during the last 7 days.
- Allergies to dragon fruit.
- Diabetes, hypertension, or renal disease.
- Medication that requires prescription.
- Pregnant or breastfeeding.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Oxford Brookes Centre for Nutrition and Health
Oxford, United Kingdom
Related Publications (1)
Flores-Verastegui MIM, Coe S, Tammam J, Almahjoubi H, Bridle R, Bi S, Thondre PS. Effects of Frozen Red Dragon Fruit Consumption on Metabolic Markers in Healthy Subjects and Individuals at Risk of Type 2 Diabetes. Nutrients. 2025 Jan 25;17(3):441. doi: 10.3390/nu17030441.
PMID: 39940297DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Sangeetha Thondre, PhD
Oxford Brookes University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Senior Lecturer
Study Record Dates
First Submitted
January 6, 2022
First Posted
January 20, 2022
Study Start
January 20, 2022
Primary Completion
August 31, 2023
Study Completion
September 1, 2023
Last Updated
September 6, 2023
Record last verified: 2023-09
Data Sharing
- IPD Sharing
- Will not share