Analysis of Outcomes and Adverse Events of Patients Undergoing Radiation Therapy
1 other identifier
observational
25,000
1 country
1
Brief Summary
Analysis of outcomes and adverse events of patients undergoing radiation therapy. Quality control using data base of patient records 2000-2025
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2000
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2000
CompletedFirst Submitted
Initial submission to the registry
August 4, 2021
CompletedFirst Posted
Study publicly available on registry
January 14, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2025
CompletedMay 21, 2025
May 1, 2025
26 years
August 4, 2021
May 17, 2025
Conditions
Outcome Measures
Primary Outcomes (2)
Overall survival (OS) and progression free survival (PFS) analysis after radiation therapy
Calculation of Overall survival (OS) and progression free survival (PFS). Time-to-event endpoints are summarized as the median and corresponding 95% confidence interval using Kaplan-Meier method
25 years
Analysis of risk factors influencing outcome after radiation therapy
Calculation of log-rank tests. If possible, hazard ratios are calculated via Cox regression. Competing risk analysis is conducted as supportive analysis
25 years
Secondary Outcomes (1)
Number of patients with acute and late adverse events after radiation therapy
25 years
Study Arms (1)
Data Base of Patient Records 2000-2025
Analysis of outcomes and adverse events
Interventions
Outcomes and adverse events using radiation therapy
Eligibility Criteria
Patients who are being treated with radiotherapy at the Department of Radiation Oncology at the Winterthur Cantonal Hospital
You may qualify if:
- Patients who are being treated with radiotherapy at the Department of Radiation Oncology at the Winterthur Cantonal Hospital
You may not qualify if:
- No radiotherapy at the Department of Radiation Oncology at the Winterthur Cantonal Hospital \<16 years,\> 105 years
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Daniel Zwahlenlead
Study Sites (1)
Kantonsspital Winterthur
Winterthur, Canton of Zurich, 8401, Switzerland
Related Publications (1)
Windisch P, Becker I, Tang H, Schroder C, Buchali A, Aebersold DM, Zwahlen DR, Forster R, Shelan M. Converting between the International Prostate Symptom Score (IPSS) and the Expanded Prostate Cancer Index Composite (EPIC) urinary subscales: modeling and external validation. BMC Urol. 2024 Feb 3;24(1):28. doi: 10.1186/s12894-024-01421-y.
PMID: 38310268DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Daniel Zwahlen, MD, MBA
Kantonsspital Winterthur KSW
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Head of Department of Radiation Oncology
Study Record Dates
First Submitted
August 4, 2021
First Posted
January 14, 2022
Study Start
January 1, 2000
Primary Completion
December 31, 2025
Study Completion
December 31, 2025
Last Updated
May 21, 2025
Record last verified: 2025-05
Data Sharing
- IPD Sharing
- Will not share