NCT05188482

Brief Summary

This article describes a case of successful treatment of a 59-year-old man with sepsis as a result of periprosthetic infection against the background of severe SARS-CoV-2-19, who was hospitalized for 59 days, 57 of which were in the intensive care unit. Vibroacoustic pulmonary therapy, the concept of noninvasive ventilation, syndrome therapy, combination antibiotic therapy taking into account the pathogen and antibiotic sensitivity were used in the treatment.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Sep 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 29, 2020

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 25, 2020

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2021

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

January 11, 2022

Completed
1 day until next milestone

First Posted

Study publicly available on registry

January 12, 2022

Completed
Last Updated

January 12, 2022

Status Verified

January 1, 2022

Enrollment Period

2 months

First QC Date

January 11, 2022

Last Update Submit

January 11, 2022

Conditions

SARS CoV 2 Infection

Keywords

periprosthetic joint infectionSARS-CoV-2co-infectionscase report.vibroacoustic therapy

Outcome Measures

Primary Outcomes (1)

  • Change of time spent on ventilation

    Changing of the time spent by patients on mechanical ventilation

    1-2 days

Interventions

vibroacoustic therapyDEVICE

Vibroacoustic respiratory therapy

Eligibility Criteria

Age59 Years - 59 Years
Sexmale
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

59-year-old man with sepsis as a result of periprosthetic infection against the background of severe SARS-CoV-2-19,

You may qualify if:

  • P/F less 300 torr
  • COVID-19 Virus Infection

You may not qualify if:

  • children
  • acute stroke
  • acute coronary syndrome
  • DVT
  • implanted pacemaker
  • rib fracture
  • infection on chest

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

NATIONAL CENTER Scientific Center of Traumatology and Orthopedics named after Academician Batpenov N.D.

Astana, 010000, Kazakhstan

Location

MeSH Terms

Conditions

COVID-19Coinfection

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Target Duration
1 Month
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 11, 2022

First Posted

January 12, 2022

Study Start

September 29, 2020

Primary Completion

November 25, 2020

Study Completion

January 1, 2021

Last Updated

January 12, 2022

Record last verified: 2022-01

Data Sharing

IPD Sharing
Will not share

Locations

KA(1)