NCT05186727

Brief Summary

The overall goal of this study is to reduce breast cancer morbidity and mortality disparities among African American women by actively engaging family history as a tool to modify screening regimens and enhance communication between women and their providers. Therefore, this rationale is reflected the project title: "You cannot change your family history, but you can change what you do with it: A peer-based education program to reduce breast cancer risk in African American women" This study will develop and test an educational curriculum that highlights the importance of knowing family history and sharing it with health care providers. The curriculum will include tools to gather family history and discuss it with providers to guide the delivery of care. The investigators will assess the effectiveness of the curriculum in group and one-on-one settings and when delivered by a Patient Ambassador (peer train-the trainer model) or a researcher. The specific objectives of the study are to: Obj. 1: Develop a CBPR-based curriculum- using a community based participatory research (CBPR) approach, that highlights the importance of family history as a risk factor for breast cancer that includes tools to collect family history information and discuss it with providers to enable a family history based screening regimen. Obj. 2: Train Patient Ambassadors- Patient Ambassadors, women from the community who act as community messengers to deliver the curriculum. Obj. 3: Pilot Implementation and Extensive Evaluation of the Curriculum- Assess two modes of delivery, group vs one-on-one, and Peer Ambassadors vs. a researcher. Obj. 4: Dissemination- of the curricular products, implementation pilot results, and implementation guides for communities and practices- via publications and other channels in preparation for grant submits to enhance the program.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
196

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2021

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

November 6, 2021

Completed
2 months until next milestone

First Posted

Study publicly available on registry

January 11, 2022

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2022

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2022

Completed
Last Updated

October 25, 2022

Status Verified

October 1, 2022

Enrollment Period

1.4 years

First QC Date

November 6, 2021

Last Update Submit

October 24, 2022

Conditions

Keywords

Family HistoryAfrican AmericanBreast Cancer Screening

Outcome Measures

Primary Outcomes (6)

  • Change in Knowledge of Genetic Screening for Breast Cancer

    The breast cancer genetic counseling knowledge questionnaire will be used to assess knowledge. This tool was validated by nurses, genetic counselors, and a group of employees.

    Baseline

  • Change in Knowledge of Genetic Screening for Breast Cancer

    The breast cancer genetic counseling knowledge questionnaire will be used to assess knowledge. This tool was validated by nurses, genetic counselors, and a group of employees.

    1 week Post Intervention

  • Change in Knowledge of Genetic Screening for Breast Cancer

    The breast cancer genetic counseling knowledge questionnaire will be used to assess knowledge. This tool was validated by nurses, genetic counselors, and a group of employees.

    3 Months Post Intervention

  • Change intention to be screened and to gather family history and share with providers

    Other items to be assessed will include attitude towards screening and family history, intent to be screened, intent to gather family history, and intent to discuss family history of breast cancer with their providers. The PRECEDE-PROCEED model will serve as a framework for the evaluation of intent to change. This model serves as a method to measure the socioecological, educational, and social epidemiological aspects of behavior change.

    Baseline

  • Change intention to be screened and to gather family history and share with providers

    Other items to be assessed will include attitude towards screening and family history, intent to be screened, intent to gather family history, and intent to discuss family history of breast cancer with their providers. The PRECEDE-PROCEED model will serve as a framework for the evaluation of intent to change. This model serves as a method to measure the socioecological, educational, and social epidemiological aspects of behavior change.

    1 week Post Intervention

  • Change intention to be screened and to gather family history and share with providers

    Other items to be assessed will include attitude towards screening and family history, intent to be screened, intent to gather family history, and intent to discuss family history of breast cancer with their providers. The PRECEDE-PROCEED model will serve as a framework for the evaluation of intent to change. This model serves as a method to measure the socioecological, educational, and social epidemiological aspects of behavior change.

    3 Months Post Intervention

Study Arms (4)

Researcher-Group

ACTIVE COMPARATOR

Education delivered in a group session by a member of the research team

Other: Family History education

Research-One on One

ACTIVE COMPARATOR

Education delivered telephonically one-on-one by a member of the research team

Other: Family History education

Patient Ambassador-Group

ACTIVE COMPARATOR

Education delivered in a group session by a Patient Ambassador (a peer mentor)

Other: Family History educationOther: Patient Ambassador

Patient Ambassador- One on One

ACTIVE COMPARATOR

Education delivered telephonically one-on-one by a Patient Ambassador (peer mentor)

Other: Family History educationOther: Patient Ambassador

Interventions

The education, developed in partnership with community partners, intends to assist women to collect family history of breast cancer and share it with their providers.

Patient Ambassador- One on OnePatient Ambassador-GroupResearch-One on OneResearcher-Group

The support of a Patient Ambassador in addition to the education is also tested.

Patient Ambassador- One on OnePatient Ambassador-Group

Eligibility Criteria

Age40 Years+
Sexfemale(Gender-based eligibility)
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years of age and older
  • Live in predominately African American communities (ZIP codes)

You may not qualify if:

  • No previous breast cancer diagnosis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

SUNY Buffalo

Buffalo, New York, 14203, United States

Location

MeSH Terms

Conditions

Genetic Predisposition to Disease

Condition Hierarchy (Ancestors)

Disease SusceptibilityDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

November 6, 2021

First Posted

January 11, 2022

Study Start

April 1, 2021

Primary Completion

August 31, 2022

Study Completion

September 30, 2022

Last Updated

October 25, 2022

Record last verified: 2022-10

Data Sharing

IPD Sharing
Will not share

Locations