Substance Use and Lifestyle-related Health Problems in Ageing Patients in OMT Treatment

NCT05182918 | Completed

• 1 other identifier: 813485
• Study Type: observational
• Target: 548
• Locations: 1 country
• Sites: 1

Brief Summary

The overall aim of the study is to explore substance use, tobacco use and lifestyle-related health problems among ageing patients in Opioid Maintenance Treatment (OMT), and other SUD treatment. The study will use already collected data from the multi-center, longitudinal, observational NorComt study (Norwegian Cohort of Patients in Opioid Maintenance Treatment and Other Drug Treatment study). NorComt is the largest longitudinal study of SUD patients in Norway. The data consists of data from OMT and other substance use disorders (SUD) treatment (N=548).

Conditions

Substance Use Disorders; Opioid Use Disorder; Tobacco Use; Health, Subjective; Mental Health Impairment

Outcome Measures

Primary Outcomes (3)

• Tobacco use

  Changes in tobacco use from baseline to follow-up

  Approximately one year after admission to treatment (range 11 - 18 months)

• Substance use

  Changes in substance use from baseline to follow-up. Excerpts from the European version were used to collect data on substance use. Substance use was scored for the previous 4 weeks on a 6-point response format were 0 corresponded to "No use" and 5 corresponded to "Daily use". 1 year follow-up were compared with baseline values.

  Approximately one year after admission to treatment (range 11 - 18 months)

• Somatic complaints.

  Changes in somatic complaints from baseline to follow-up. A checklist containing 16 somatic complaints common among chronic drug users, including major organ systems. Responses are provided on a 0 -4 response format, with 0 corresponding to "not at all", 1 "a little", 2 "moderately", 3 "a lot", and 4 "very much".

  Approximately one year after admission to treatment (range 11 - 18 months).

Secondary Outcomes (2)

• Mental distress

  Approximately one year after admission to treatment (range 11 - 18 months)

• QoL (quality of life)

  Approximately one year after admission to treatment (range 11 - 18 months)

Study Arms (1)

Patients in OMT and other SUD treatment

Patients in opioid maintenance treatment and other substance use disorder treatment

Other: Substance use disorder treatment

Interventions

Substance use disorder treatment OTHER

The study followed a heterogenous sample of patients in opioid maintenance treatment (OMT) and other substance use disorder treatment. The main focus was on health related problems in this cohort, with focus on tobacco use and substance use.

Patients in OMT and other SUD treatment

Eligibility Criteria

• Age: 18 Years - 99 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients were included in the study from 21 participating treatment facilities across Norway, 14 were opioid maintenance treatment (OMT) outpatient centers, and 7 were inpatient centers (predominately non-OMT). Apart from an established opioid use disorder diagnosis there are no further criteria for entering OMT treatment, although generally substitution free treatment is recommended as a first option. In-patient SUD treatment represented in the present project typically has a duration of 6-9 months, primarily with non-OMT treatment in therapeutic community-like settings. Some patients would transfer to an outpatient treatment after completing in-patient treatment.

You may qualify if:

• Admittance to a substance use disorder treatment facility, either standardized opioid maintenance treatment (OMT) or other substance use disorder treatment (in-patient)

You may not qualify if:

• None

Sponsors & Collaborators

• Sorlandet Hospital HF: lead
• University of Oslo: collaborator

Study Sites (1)

Addiction Unit - Sørlandet Hospital

Kristiansand, Agder, 4600, Norway

Location

Related Publications (2)

• Bjornestad ED, Vederhus JK, Clausen T. Change in substance use among patients in opioid maintenance treatment: baseline to 1-year follow-up. Harm Reduct J. 2024 May 24;21(1):101. doi: 10.1186/s12954-024-01005-x.

  PMID: 38790008 DERIVED

• Bjornestad ED, Vederhus JK, Clausen T. Change in self-reported somatic symptoms among patients in opioid maintenance treatment from baseline to 1-year follow-up. BMC Psychiatry. 2024 Feb 21;24(1):149. doi: 10.1186/s12888-024-05590-w.

  PMID: 38383345 DERIVED

MeSH Terms

Conditions

Substance-Related Disorders; Opioid-Related Disorders; Tobacco Use

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders; Mental Disorders; Narcotic-Related Disorders; Behavior

Study Officials

• Thomas Clausen, PhD

  Norwegian Centre for Addiction Research, University of Oslo

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 22, 2021
• First Posted: January 10, 2022
• Study Start: December 1, 2012
• Primary Completion: August 31, 2016
• Study Completion: August 31, 2016
• Last Updated: June 8, 2023

Record last verified: 2021-12

Locations

NO (1)